Man pages for OptimalGoldstandardDesigns
Design Parameter Optimization for Gold-Standard Non-Inferiority Trials
| calc_ASN | Helper function to calculate the average sample size |
| calc_ASNP | Calculate the average placebo group sample size |
| calc_c | Helper function to calculate allocation ratios from stagewise... |
| calc_conditional_local_rejection_probs | Calculate the (local) conditional type I errors of both... |
| calc_conditional_power | Calculate the conditional power to reject both hypothesis... |
| calc_cumc | Helper function to calculate "cumulative allocation ratio"... |
| calc_cumn | Helper function to calculate cumulative sample sizes from... |
| calc_final_state_probs | Helper function to calculate the final state probabilities |
| calc_gamma | Helper function to calculate gamma factors from group... |
| calc_local_alphas | Helper function to calculate the local type I error rates of... |
| calc_local_rejection_boundaries | Helper function to calculate the local rejection boundaries... |
| calc_mu_vec | Helper function to calculate expected value of normal test... |
| calc_mu_wo_nT1 | Helper function to calculate expected value of normal test... |
| calc_n_from_c | Helper function to calculate other n's given n_1,T and... |
| calc_nT1_wrt_bTC2e | Helper function to calculate the required sample size (of the... |
| calc_prob_reject_both | Helper function to calculate the probability to reject both... |
| calc_prob_reject_both_singlestage | Helper function to calculate the probability to reject both... |
| calc_Sigma | Helper function to calculate the covariance matrix from the... |
| calc_worst_type_I_error | Helper function to calculate the maximal probability of... |
| conditional_mean | Calculate the conditional mean of a multivariate normal... |
| conditional_Sigma | Calculate the conditional mean of a multivariate normal... |
| objective_onestage | Objective function for single-stage gold-standard designs |
| objective_twostage | Objective function for two-stage gold-standard designs |
| OptimalGoldstandardDesigns | OptimalGoldstandardDesigns |
| optimize_design_onestage | Calculate optimal design parameters for a single-stage... |
| optimize_design_twostage | Calculate optimal design parameters for a two-stage... |
| padd_whitespace | Add whitespace padding to string |
| pmvnorm_ | mvtnorm::pmvnorm, but returns 0 if any lower boundary is... |
| pmvt_ | mvtnorm::pmvt, but returns 0 if any lower boundary is larger... |
| print.OneStageGoldStandardDesign | Printing method for optimal single-stage goldstandard designs |
| print.TwoStageGoldStandardDesign | Printing method for optimal two-stage goldstandard designs |
