calc_conditional_local_rejection_probs: Calculate the (local) conditional type I errors of both...

In OptimalGoldstandardDesigns: Design Parameter Optimization for Gold-Standard Non-Inferiority Trials

Calculate the (local) conditional type I errors of both hypothesis given both interim test statistics.

Description

Calculate the (local) conditional type I errors of both hypothesis given both interim test statistics.

Usage

calc_conditional_local_rejection_probs(Z_TP1, Z_TC1, D, mu_vec = D$mu_vec$H0)

Arguments

Z_TP1	First stage Z-test statistic of the superiority test of treatment over placebo.
Z_TC1	First stage Z-test statistic of the non-inferiority test of treatment to the active control.
D	list containing all parameters of a the trial design.
mu_vec	vector of means of the test statistic c(Z_TP1, Z_TP2, Z_TC1, Z_TC1).

Value

named numeric vector with both conditional type I errors.

OptimalGoldstandardDesigns documentation built on Sept. 11, 2023, 5:09 p.m.