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POSTm: Phylogeny-Guided OTU-Specific Association Test for Microbiome Data
Implements the Phylogeny-Guided Microbiome OTU-Specific Association Test method, which boosts the testing power by adaptively borrowing information from phylogenetically close OTUs (operational taxonomic units) of the target OTU. This method is built on a kernel machine regression framework and allows for flexible modeling of complex microbiome effects, adjustments for covariates, and can accommodate both continuous and binary outcomes.
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Package details |
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| Author | Caizhi Huang [aut], Jung-Ying Tzeng [aut], Shannon T. Holloway [aut, cre] |
| Maintainer | Shannon T. Holloway <shannon.t.holloway@gmail.com> |
| License | GPL-2 |
| Version | 1.4 |
| Package repository | View on CRAN |
| Installation |
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