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PQLseq: Efficient Mixed Model Analysis of Count Data in Large-Scale Genomic Sequencing Studies
An efficient tool designed for differential analysis of large-scale RNA sequencing (RNAseq) data and Bisulfite sequencing (BSseq) data in the presence of individual relatedness and population structure. 'PQLseq' first fits a Generalized Linear Mixed Model (GLMM) with adjusted covariates, predictor of interest and random effects to account for population structure and individual relatedness, and then performs Wald tests for each gene in RNAseq or site in BSseq.
Getting started
Browse package contents
Package details |
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| Author | Shiquan Sun, Jiaqiang Zhu, Xiang Zhou |
| Maintainer | Jiaqiang Zhu <jiaqiang@umich.edu> |
| License | GPL (>= 2) |
| Version | 1.2.1 |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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Try the PQLseq package in your browser
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