PharmPow_crossover: Pharmacometric power calculations for mixed crossover study...

In PharmPow: Pharmacometric Power calculations for mixed study designs

Description

This function performs power calculations for mixed crossover study designs. The input data for these functions is taylored for NONMEM .phi files.

Usage

PharmPow_crossover(datafullA, datareducedA, datafullB, datareducedB, 
                   maxIDsA = 200, maxIDsB = 200, nresamples = 10000, 
                   power = 80, 
                   designAlab = "Number of patients sampling design A", 
                   designBlab = "Number of patients sampling design B")

Arguments

datafullA	The (NONMEM).phi file from the full model fitted on design A can be defined here
datareducedA	The (NONMEM).phi file from the reduced model fitted on design A can be defined here
datafullB	The (NONMEM).phi file from the full model fitted on design B can be defined here
datareducedB	The (NONMEM).phi file from the reduced model fitted on design B can be defined here
maxIDsA	The maximum number of ID's for design A can be defined here (default is 200)
maxIDsB	The maximum number of ID's for design B can be defined here (default is 200)
nresamples	The number of resamples (different study designs) can be defined here (default is 10000)
power	The target power for the study designs can be defined here (default is 80%)
designAlab	The label for design A can be defined here (default is "Number of patients sampling design A"")
designBlab	The label for design B can be defined here (default is "Number of patients sampling design B")

Author(s)

Frank Kloprogge & Joel Tarning

Examples

# Power calculations for a mixed study design (for design C & D)
## Not run: PharmPow_crossover(datafullA=system.file("extdata","designC_full",
                                                  package="PharmPow"), 
                            datareducedA=system.file("extdata","designC_red",
                                                     package="PharmPow"), 
                            datafullB=system.file("extdata","designD_full",
                                                  package="PharmPow"), 
                            datareducedB=system.file("extdata","designD_red",
                                                     package="PharmPow"))

## End(Not run)                                            

PharmPow documentation built on May 2, 2019, 2:07 a.m.