biosensor.eq | R Documentation |
nlsLM
Calculates the values of biosensor response model for given time points and response parameters.
biosensor.eq(x, y.min, y.max, K, n)
x |
A vector of concentration values |
y.min |
The minimum fluorescence value |
y.max |
The maximum fluorescence value |
K |
Sensitivity parameter |
n |
Cooperativity parameter |
A vector of fluorescence values
Meyer, A.J., Segall-Shapiro, T.H., Glassey, E. et al. Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors. Nat Chem Biol 15, 196–204 (2019). DOI: 10.1038/s41589-018-0168-3
n <- seq(1:10)
conc <- rev(10*(1/2)^n)
fit <- biosensor.eq(conc, 300, 82000, 0.85, 2)
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