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RAS: Regional Association Score for Genome-Wide Association Studies
Implements the Regional Association Score (RAS) method for genome-wide association studies (GWAS). For each single nucleotide polymorphism (SNP), RAS quantifies the strength of association within its surrounding genomic region, arranges these regional scores along the chromosome into a signal profile, and applies changepoint detection to locate association regions, improving statistical power while controlling the false positive rate. The method is described in Jiang and Zhang (2025) <doi:10.1073/pnas.2419721122>.
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Package details |
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| Author | Yiran Jiang [aut], Jiahe Jin [aut, cre], Heping Zhang [aut] |
| Maintainer | Jiahe Jin <jiahe.jin@yale.edu> |
| License | MIT + file LICENSE |
| Version | 1.0.3 |
| URL | https://github.com/hepingzhangyale/RAS |
| Package repository | View on CRAN |
| Installation |
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