IST | R Documentation |
The International Stroke Trial Dataset
IST
A data frame with 19435 rows and 112 columns:
Randomisation data: Age in years
Other data and derived variables: Compliant for aspirin
Other data and derived variables: Compliant for heparin
Other data and derived variables: Country code
Other data and derived variables: Abbreviated country code
Recurrent stroke within 14 days: Discharged alive from hospital
Recurrent stroke within 14 days: Date Discharged alive from hospital
Data collected on 14 day/discharge form about treatments given in hospital: Non trial antiplatelet drug (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Aspirin given for 14 days or till death or discharge (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Discharged on long term aspirin (Y/N)
Randomisation data: Estimate of local day of week (assuming RDATE is Oxford)
Data collected on 14 day/discharge form about treatments given in hospital: Calcium antagonists (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Carotid surgery (Y/N)
Other events within 14 days: Dead on discharge form
Other events within 14 days: Cause of death (1-Initial stroke/2-Recurrent stroke (ischaemic or unknown /3-Recurrent stroke (haemorrhagic)/4-Pneumonia /5-Coronary heart disease/6-Pulmonary embolism /7-Other vascular or unknown/8-Non-vascular/0-unknown)
Date of dead on discharge form (yyyy/mm/dd); NOTE: this death is not necessarily within 14 days of randomisation
Other events within 14 days: Comment on death
Final diagnosis of initial event: Haemorrhagic stroke
Final diagnosis of initial event: Ischaemic stroke
Final diagnosis of initial event: Indeterminate stroke
Indicator variables for specific causes of death: Initial stroke
Indicator variables for specific causes of death: Reccurent ischaemic/unknown stroke
Indicator variables for specific causes of death: Reccurent haemorrhagic stroke
Indicator variables for specific causes of death: Pneumonia
Indicator variables for specific causes of death: Coronary heart disease
Indicator variables for specific causes of death: Pulmonary embolism
Indicator variables for specific causes of death: Other vascular or unknown
Indicator variables for specific causes of death: Non vascular
Data collected on 14 day/discharge form about treatments given in hospital: Glycerol or manitol (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Haemodilution (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Medium dose heparin given for 14 days etc in pilot (combine with above)
Other data and derived variables: Indicator variable for death (1=died; 0=did not die)
Data collected on 14 day/discharge form about treatments given in hospital: Non trial intravenous heparin (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Low dose heparin given for 14 days or till death/discharge (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Major non-cerebral haemorrhage (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Date of Major non-cerebral haemorrhage (yyyy/mm/dd)
Data collected on 14 day/discharge form about treatments given in hospital: Comment of Major non-cerebral haemorrhage
Data collected on 14 day/discharge form about treatments given in hospital: Date of Major non-cerebral haemorrhage (yyyy/mm/dd)
Final diagnosis of initial event: Not a stroke
Final diagnosis of initial event: Comment on Not a stroke
Data collected on 14 day/discharge form about treatments given in hospital: Other anticoagulants (Y/N)
Other events within 14 days: Pulmonary embolism
Other events within 14 days: Date of Pulmonary embolism (yyyy/mm/dd)
Other events within 14 days: Discharge destination (A-Home /B-Relatives home /C-Residential care /D-Nursing home /E-Other hospital departments /U-Unknown)
Recurrent stroke within 14 days: Haemorrhagic stroke
Recurrent stroke within 14 days: Date of Haemorrhagic stroke (yyyy/mm/dd)
Recurrent stroke within 14 days: Ischaemic recurrent stroke
Recurrent stroke within 14 days: Date of Ischaemic recurrent stroke (yyyy/mm/dd)
Recurrent stroke within 14 days: Unknown type
Recurrent stroke within 14 days: Date of Unknown type (yyyy/mm/dd)
Data collected on 14 day/discharge form about treatments given in hospital: Non trial subcutaneous heparin (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Other side effect (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Date of Other side effect
Data collected on 14 day/discharge form about treatments given in hospital: Comment of Other side effect
Data collected on 14 day/discharge form about treatments given in hospital: Steroids (Y/N)
Data collected on 14 day/discharge form about treatments given in hospital: Thrombolysis (Y/N)
Indicator variables for specific causes of death: Indicator of deep vein thrombosis on discharge form
Other data and derived variables: Predicted probability of death at 14 days
Other data and derived variables: Predicted probability of death at 6 month
Other data and derived variables: Predicted probability of death/dependence at 6 month
Data collected at 6 months: On antiplatelet drugs
Data collected at 6 months: Dead at six month follow-up (Y/N)
Data collected at 6 months: Cause of death (1-Initial stroke /2-Recurrent stroke (ischaemic or unknown) /3-Recurrent stroke (haemorrhagic) /4-Pneumonia /5-Coronary heart disease /6-Pulmonary embolism /7-Other vascular or unknown /8-Non-vascular /0-unknown)
Data collected at 6 months: Date of death; NOTE: this death is not necessarily within 6 months of randomisation
Data collected at 6 months: Comment on death
Data collected at 6 months: Dependent at 6 month follow-up (Y/N)
Data collected at 6 months: Date of last contact
Data collected at 6 months: On anticoagulants
Data collected at 6 months: Place of residance at 6 month follow-up ( A-Home /B-Relatives home /C-Residential care /D-Nursing home /E-Other hospital departments /U-Unknown)
Data collected at 6 months: Fully recovered at 6 month follow-up (Y/N)
Other data and derived variables: Date discharge form completed
Other data and derived variables: Date discharge form received
Other data and derived variables: Date 6 month follow-up done
Indicator variables for specific causes of death: Cerebral bleed/heamorrhagic stroke within 14 days; this is slightly wider definition than DRSH an is used for analysis of cerebral bleeds
Randomisation data: Hospital number
Randomisation data: Local time – hours
Indicator variables for specific causes of death: Indicator of haemorrhagic transformation within 14 days
Other data and derived variables: Indicator of death at 14 days
Indicator variables for specific causes of death: Indicator of ischaemic stroke within 14 days
Randomisation data: Local time – minutes
Indicator variables for specific causes of death: Indicator of any non-cerebral bleed within 14 days
Other data and derived variables: Coding of compliance (see Table 3) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1186/1745-6215-13-24")}
Indicator variables for specific causes of death: Indicator of indeterminate stroke within 14 days
Other data and derived variables: Six month outcome ( 1-dead /2-dependent /3-not recovered /4-recovered /8 or 9 – missing status
Data collected on 14 day/discharge form about treatments given in hospital: Estimate of time in days on trial treatment
Indicator variables for specific causes of death: Indicator of pulmonary embolism within 14 days
Randomisation data: Aspirin within 3 days prior to randomisation (Y/N)
Randomisation data: Atrial fibrillation (Y/N); not coded for pilot phase - 984 patients
Randomisation data: Conscious state at randomisation (F - fully alert, D - drowsy, U - unconscious)
Randomisation data: CT before randomisation (Y/N)
Randomisation data: Date of randomisation
Randomisation data: Face deficit (Y/N/C=can't assess)
Randomisation data: Arm/hand deficit (Y/N/C=can't assess)
Randomisation data: Leg/foot deficit (Y/N/C=can't assess)
Randomisation data: Dysphasia (Y/N/C=can't assess)
Randomisation data: Hemianopia (Y/N/C=can't assess)
Randomisation data: Visuospatial disorder (Y/N/C=can't assess)
Randomisation data: Brainstem/cerebellar signs (Y/N/C=can't assess)
Randomisation data: Other deficit (Y/N/C=can't assess)
Randomisation data: Delay between stroke and randomisation in hours
Randomisation data: Heparin within 24 hours prior to randomisation (Y/N)
Randomisation data: Systolic blood pressure at randomisation (mmHg)
Randomisation data: Symptoms noted on waking (Y/N)
Randomisation data: Infarct visible on CT (Y/N)
Randomisation data: Trial aspirin allocated (Y/N)
Randomisation data: Trial heparin allocated (M/L/N) \[M is coded as H=high in pilot\]
Other data and derived variables: Know to be dead or alive at 14 days (1=Yes, 0=No); this does not necessarily mean that we know outcome at 6 monts – see OCCODE for this
Randomisation data: M=male; F=female
Indicator variables for specific causes of death: Indicator of any stroke within 14 days
Randomisation data: Stroke subtype (TACS/PACS/POCS/LACS/other)
Other data and derived variables: Time of death or censoring in days
Indicator variables for specific causes of death: Indicator of major non-cerebral bleed within 14 days
...
Obtained from Sandercock, Peter; Niewada, Maciej; Czlonkowska, Anna. (2011). International Stroke Trial database (version 2), [dataset]. University of Edinburgh. Department of Clinical Neurosciences. \Sexpr[results=rd]{tools:::Rd_expr_doi("https://doi.org/10.7488/ds/104")} Under ODC-by licence
Sandercock P et al. Peter.Sandercock@ed.ac.uk
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.