Variations of Remove Unwanted Variation-III (RUV-III) known as RUV-III-C (RUV-III Complete). RUV-III performs normalisation using negative control variables and replication. RUV-III-C extends this method to cases where the data contains missing values, by applying RUV-III to complete subsets of the data. Originally designed for SWATH-MS proteomics datasets. Poulos et al. (2020) <doi:10.1038/s41467-020-17641-3>.

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Package details

AuthorRohan Shah [aut, cre], Sean Peters [ctb], Qing Zhong [ctb], Children's Medical Research Institute [cph]
MaintainerRohan Shah <>
LicenseMIT + file LICENSE
Package repositoryView on CRAN
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RUVIIIC documentation built on April 23, 2021, 5:07 p.m.