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Variations of Remove Unwanted Variation-III (RUV-III) known as RUV-III-C (RUV-III Complete). RUV-III performs normalisation using negative control variables and replication. RUV-III-C extends this method to cases where the data contains missing values, by applying RUV-III to complete subsets of the data. Originally designed for SWATH-MS proteomics datasets. Poulos et al. (2020) <doi:10.1038/s41467-020-17641-3>.
Package details |
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Author | Rohan Shah [aut, cre], Sean Peters [ctb], Qing Zhong [ctb], Children's Medical Research Institute [cph] |
Maintainer | Rohan Shah <rshah@cmri.org.au> |
License | MIT + file LICENSE |
Version | 1.0.19 |
Package repository | View on CRAN |
Installation |
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