It provides a list of genes associated to diseases (g2d$clean and g2d$complete) based on the following 4 publications (GS2D, Fontaine (2016) <doi:10.18547/gcb.2016.vol2.iss1.e33>, DisGeNET, Pinero (2016) <doi:10.1093/nar/gkw943> Berto2016, Berto (2016) <doi:10.3389/fgene.2016.00031> and PsyGeNET, Sacristan (2015) <doi:10.1093/bioinformatics/btv301>). Those lists were combined and manually curated to have matching disease names. When provided a list of gene names, it calculates the disease enrichment of the gene set. The enrichment is calculated using proportion test and Fisher's exact test. Adjusted fdr p-values are returned alongside with p-values combined using the Fisher's method.
Package details |
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Author | Deisy Morselli Gysi and Katja Nowick |
Maintainer | Deisy Morselli Gysi <deisy@bioinf.uni-leipzig.de> |
License | GPL-2 |
Version | 1.0.0 |
Package repository | View on CRAN |
Installation |
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