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An implementation of calculating the R-squared measure as a total mediation effect size measure and its confidence interval for moderate- or high-dimensional mediator model. It gives an option to filter out non-mediators using variable selection method. The original R package is directly related to the paper "Estimation of mediation effect for high-dimensional omics mediators with application to the Framingham Heart Study" with <doi:10.1101/774877>. The new version contains a choice of using cross-fitting, which is computationally faster.
Package details |
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Author | Tianzhong Yang [aut, cre] |
Maintainer | Tianzhong Yang <yang3704@umn.edu> |
License | GPL-3 |
Version | 0.2.1.0 |
Package repository | View on CRAN |
Installation |
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