Man pages for SimTOST
Sample Size Estimation for Bio-Equivalence Trials Through Simulation
| as.numeric.simss_mielke | Coerce a Mielke result to a numeric sample size |
| check_equivalence | Check Equivalence for Multiple Endpoints |
| confint.countpower | Extract the Monte Carlo confidence interval from count power... |
| confint.simpower | Extract the Monte Carlo confidence interval from... |
| confint.simss | Confidence Interval for Achieved Power from simss object |
| derive_allocation_rate | Derive and Validate Treatment Allocation Rate (TAR) |
| derive_arm_names | Derive or Assign Arm Names |
| derive_endpoint_names | Derive Endpoint Names |
| derive_varcov_list | Derive Variance-Covariance Matrix List |
| dot-normalize_internal_distribution | Calculate the power across all comparators |
| dot-plot_correlation | Plot simulated endpoint correlations |
| dot-power_count_joint_serial | Estimate joint power for correlated count endpoints and... |
| dot-power_count_serial | Estimate power for count-rate equivalence |
| dot-select_power_plot_n | Select the smallest plotted sample size that reaches the... |
| get_par | Parameter Configuration for Endpoints and Comparators |
| info_msg | Helper function for conditional messages |
| plot.countpower | Plot count-outcome power results |
| plot.countss | Plot count-outcome sample-size results |
| plot_decision_heatmap | Plot simulated decision heatmaps |
| plot_distribution | Plot distributions of retained simulated observations |
| plot_mc_error | Plot Monte Carlo error |
| plot.simpower | Plot fixed-sample-size power results |
| plot.simpower_curve | Plot fixed-sample-size power results |
| plot.simss | Plot Power vs Sample Size for Simulation Results |
| plot_stability | Plot simulation stability |
| plot.type1error | Plot empirical Type I error |
| plot.type1error_joint | Plot joint Type I error scenarios |
| power_dom | Power Calculation for Difference of Means (DOM) Hypothesis... |
| power_Mielke | Power Calculation for Hypothesis Testing in Equivalence... |
| prepare_joint_count_inputs | Prepare inputs for a joint multi-arm count simulation |
| print.countpower | Print count-outcome power results |
| print.countss | Print count-outcome sample-size results |
| print.simpower | Print fixed-sample-size power results |
| print.simss | Print Summary of Sample Size Estimation |
| print.simss_mielke | Print a Mielke sample-size result |
| ptv | Compute p-values for a t-distribution with Fixed Degrees of... |
| ptvdf | Calculate p-values using t-distribution with Variable Degrees... |
| run_simulations | Run a design-specific simulation |
| run_simulations_2x2_dom | Run Simulations for a 2x2 Crossover Design with Difference of... |
| run_simulations_2x2_rom | Run Simulations for a 2x2 Crossover Design with Ratio of... |
| run_simulations_par_dom | Run Simulations for a Parallel Design with Difference of... |
| run_simulations_par_rom | Run Simulations for a Parallel Design with Ratio of Means... |
| sampleSize | Sample Size Calculation for Bioequivalence and Multi-Endpoint... |
| sampleSize_count | Estimate sample size for count-rate equivalence |
| sampleSize_count_joint | Estimate sample size for joint correlated count equivalence |
| sampleSize_Mielke | Sample Size Estimation for Multiple Hypothesis Testing Using... |
| sign_Mielke | Simulated Test Statistic for Noninferiority/Equivalence... |
| simParallelEndpoints | Generate Simulated Endpoint Data for Parallel Group Design |
| simPower | Estimate power at a fixed sample size |
| SimTOST | Sample Size Estimation via Simulation |
| sub-.simss_mielke | Preserve named-vector indexing for legacy Mielke examples |
| summary.countpower | Summarize count-outcome power results |
| summary.countss | Summary for Count Sample-Size Results |
| summary.simpower | Summarize fixed-sample-size power results |
| summary.simss | Summary for Simulation Results |
| test_2x2_dom | Simulate a 2x2 Crossover Design and Compute Difference of... |
| test_2x2_rom | Simulate a 2x2 Crossover Design and Compute Ratio of Means... |
| test_par_dom | Simulate a Parallel Design and Test Difference of Means (DOM) |
| test_par_rom | Simulate a Parallel Design and Test Ratio of Means (ROM) |
| test_studies | test_studies |
| type1Error | Empirical Type I Error at the Least-Favorable Null |
| uniroot.integer.mod | Optimizer for Uniroot Integer (Modified) |
| update.countpower | Update a standalone count power calculation |
| update.countss | Update a standalone count sample-size calculation |
| update.simpower | Update a SimTOST fixed-sample-size power calculation |
| update.simss | Update a SimTOST sample-size calculation |
| validate_positive_definite | Validate Positive Semi-Definite Matrices |
| validate_sample_size_limits | Check Sample Size Limits |
