Estimation of twostate (survival) models and irreversible illness death models with possibly intervalcensored,lefttruncated and rightcensored data. Proportional intensities regression models can be specified to allow for covariates effects separately for each transition. We use either a parametric approach with Weibull baseline intensities or a semiparametric approach with Msplines approximation of baseline intensities in order to obtain smooth estimates of the hazard functions. Parameter estimates are obtained by maximum likelihood in the parametric approach and by penalized maximum likelihood in the semiparametric approach.
Package details 


Author  Celia Touraine, Pierre Joly, Thomas A. Gerds 
Maintainer  Thomas Alexander Gerds <tag@biostat.ku.dk> 
License  GPL (>= 2) 
Version  1.4.1 
Package repository  View on CRAN 
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