Estimation of twostate (survival) models and irreversible illness death models with possibly intervalcensored, lefttruncated and rightcensored data. Proportional intensities regression models can be specified to allow for covariates effects separately for each transition. We use either a parametric approach with Weibull baseline intensities or a semiparametric approach with Msplines approximation of baseline intensities in order to obtain smooth estimates of the hazard functions. Parameter estimates are obtained by maximum likelihood in the parametric approach and by penalized maximum likelihood in the semiparametric approach.
Package details 


Author  Celia Touraine [aut], Thomas Alexander Gerds [aut, cre], Pierre Joly [aut] (Author and maintainer of the Fortran code), Cecile ProustLima [aut] (Author of the Fortran code), Helene JacqminGadda [aut] (Author of the Fortran code), Amadou Diakite [aut] (Author of the Fortran code), W.D. Cody [aut] (Author of the Fortran code), A.H. Morris [aut] (Author of the Fortran code), B.W. Brown [aut] (Author of the Fortran code), Robin Genuer [ctb] 
Maintainer  Thomas Alexander Gerds <tag@biostat.ku.dk> 
License  GPL (>= 2) 
Version  2024.04.10 
Package repository  View on CRAN 
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