SubgrpID: Patient Subgroup Identification for Clinical Drug Development

Implementation of Sequential BATTing (bootstrapping and aggregating of thresholds from trees) for developing threshold-based multivariate (prognostic/predictive) biomarker signatures. Variable selection is automatically built-in. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output. Detail algorithms are described in Huang et al (2017) <doi:10.1002/sim.7236>.

Getting started

Package details

AuthorXin Huang [aut, cre, cph], Yan Sun [aut], Saptarshi Chatterjee [aut], Paul Trow [aut]
MaintainerXin Huang <xin.huang@abbvie.com>
LicenseGPL (>= 2)
Version0.12
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("SubgrpID")

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SubgrpID documentation built on May 29, 2024, 1:33 a.m.