Description Usage Arguments Author(s) References
teqr.MTDdatatox takes the simData and DLdata output and creates the MTD level data.
1 | teqr.MTDdataconACT(simData = simData, DLdata = DLdata)
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simData |
includes the simulation results data, cohortSize,proba,probc, MTDss,pTarget,lowerlimit,upperlimit,tootoxic, toxcon, llactivity, number of simulations (sim) |
DLdata |
simNo,doselevel,stox (no of subjects experiencing activity),dllength (length of the cohort),toxl (lower 95% CI),toxu (upper 95% CI) ,toxCest (toxicity estimate) |
M.S. Blanchard <sblanchard@coh.org>
Blanchard MS and Longmate JA, (2011). Toxicity equivalence range design (TEQR): A practical Phase I design. Contemporary Clinical Trials,(32), 114-121.
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