TopDom: An Efficient and Deterministic Method for Identifying Topological Domains in Genomes

The 'TopDom' method identifies topological domains in genomes from Hi-C sequence data (Shin et al., 2016 <doi:10.1093/nar/gkv1505>). The authors published an implementation of their method as an R script (two different versions; also available in this package). This package originates from those original 'TopDom' R scripts and provides help pages adopted from the original 'TopDom' PDF documentation. It also provides a small number of bug fixes to the original code.

Getting started

Package details

AuthorHenrik Bengtsson [aut, cre, cph], Hanjun Shin [aut, ctr, cph], Harris Lazaris [ctr, cph] (PhD Student, NYU), Gangqing Hu [ctr, cph] (Staff Scientist, NIH), Xianghong Zhou [ctr]
MaintainerHenrik Bengtsson <>
Package repositoryView on CRAN
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TopDom documentation built on May 6, 2021, 9:07 a.m.