TriadSim: Simulating Triad Genomewide Genotypes
Version 0.1.1

Simulate genotypes for case-parent triads, case-control, and quantitative trait samples with realistic linkage diequilibrium structure and allele frequency distribution. For studies of epistasis one can simulate models that involve specific SNPs at specific sets of loci, which we will refer to as "pathways". TriadSim generates genotype data by resampling triad genotypes from existing data. The details of the method is described in the manuscript under preparation "Simulating Autosomal Genotypes with Realistic Linkage Disequilibrium and a Spiked in Genetic Effect" Shi, M., Umbach, D.M., Wise A.S., Weinberg, C.R.

Package details

AuthorMin Shi [aut, cre]
Bioconductor views snpStats
Date of publication2017-05-25 00:00:45 UTC
MaintainerMin Shi <[email protected]>
LicenseGPL-3
Version0.1.1
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("TriadSim")

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TriadSim documentation built on May 29, 2017, 8:13 p.m.