waning_hr: Compute effective hazard ratio with treatment waning

In WARDEN: Workflows for Health Technology Assessments in R using Discrete EveNts

Compute effective hazard ratio with treatment waning

Description

Returns the effective hazard ratio at a given time on treatment, accounting for waning of treatment effect.

Usage

waning_hr(base_hr, time_on_tx, start, duration, type = "linear")

Arguments

base_hr	Numeric. Initial treatment HR (< 1 means benefit).
time_on_tx	Numeric. Time the patient has been on treatment.
start	Numeric. Time at which waning begins (HR = base_hr before this).
duration	Numeric. Duration of the waning period (HR reaches 1 at start + duration).
type	Character. Waning function: "linear" (default), "exponential", or "instant".

Value

Numeric scalar: effective HR at time_on_tx.

WARDEN documentation built on July 23, 2026, 5:08 p.m.