YPInterimTesting-package: Interim Monitoring Using Adaptively Weighted Log-rank Test in...

In YPInterimTesting: Interim Monitoring Using Adaptively Weighted Log-Rank Test in Clinical Trials

Description

This package provides monitoring boundary for interim testing using the adaptively weighted log-rank test developed by Yang and Prentice (2010). It is shown in Yang (2018) that the adaptively weighted log-rank test is asymptotically fully efficient when the limiting censoring distributions in two groups are equal. For a given spending function, the main function of the package ypinterim provides stopping boundaries at the interim looks, along with nominal p-values. The object being returned by the function ypinterim can be formatted to a table using the function summary.

Details

Package:	YPInterimTesting
Type:	Package
Version:	1.0.0
Date:	2018-10-31
License:	GPL (>= 3)

Author(s)

Daewoo Pak and Song Yang

References

Yang, S. (2018). Interim monitoring using the adaptively weighted log-rank test in clinical trials for survival outcomes. Statistics in Medicine. <doi:10.1002/sim.7958>

Yang, S., & Prentice, R. (2010). Improved logrank-type tests for survival data using adaptive weights. Biometrics, 66(1), 30-38.

See Also

ypinterim

YPInterimTesting documentation built on June 7, 2019, 5:02 p.m.