adaptiveGPCA-package | R Documentation |
This package implements the methods for structured dimensionality reduction described in Fukuyama, J. (2017). The general idea is to obtain a low-dimensional representation of the data, similar to that given by PCA, which incorporates side information about the relationships between the variables. The output is similar to a PCA biplot, but the variable loadings are regularized so that similar variables are encouraged to have similar loadings on the principal axes.
There are two main ways of using this package. The function
adaptivegpca
will choose how much to regularize the
variables according to the similarities between them, while the
function gpcaFullFamily
produces analogous output for
a range of regularization parameters. With this function, the
results for the different regularization parameters are inspected
with the visualizeFullFamily
function, and the
desired parameter is chosen manually.
The package also contains functionality to integrate with phyloseq:
the function processPhyloseq
takes a
phyloseq
object and creates the inputs
necessary to perform adaptive gPCA on a microbiome dataset
including information about the phylogenetic relationships between
the bacteria.
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