Methods to evaluate the performance characteristics of various point and interval estimators for optimal adaptive two-stage designs as described in Meis et al. (2024) <doi:10.1002/sim.10020>. Specifically, this package is written to work with trial designs created by the 'adoptr' package (Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09>; Pilz et al. (2021) <doi:10.1002/sim.8953>)). Apart from the a priori evaluation of performance characteristics, this package also allows for the evaluation of the implemented estimators on real datasets, and it implements methods to calculate p-values.
Package details |
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Author | Jan Meis [aut, cre] (<https://orcid.org/0000-0001-5407-7220>), Martin Maechler [cph] (<https://orcid.org/0000-0002-8685-9910>, Original author of monoSpl.c (from the 'stats' package).) |
Maintainer | Jan Meis <meis@imbi.uni-heidelberg.de> |
License | GPL (>= 2) |
Version | 1.0.0 |
URL | https://jan-imbi.github.io/adestr/ |
Package repository | View on CRAN |
Installation |
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