horm.cort | R Documentation |
The horm.cort
data frame has 425 rows and 4 columns of data representing measurement of cortisol on 36 individuals.
data(horm.cort)
The data frame contains the following columns:
ID a vector of index indicating individuals on whom measures were made.
time a numeric vector of time points of every 2 hours in 24 hours. The time is scaled into [0, 1].
type a vector of character strings identifying the groups, "normal", "depressed", or "cushing", which the individuals belong to.
conc cortisol concentration measurements in log10
scale.
Blood samples were collected every 2 hours for 24 hours from three group of healthy normal volunteers and volunteers with depresession and suchsing syndrome. They were analyzed for parameters that measure hormones of the hypothalamic-pituitary axix. Human circadian thythm is one of the research objective. In this data set, only measurements of cortisol concetration were included.
This data set was extracted from a stress study conducted in the medical center of the University of Michigan.
Wang, Y. and Brown, M. B. (1996). A Flexible Model for Human Circadian Rhythms. Biometrics 52, 588-596.
Yuedong Wang, Chunlei Ke and Morton B. Brown (2003), Shape Invariant Modelling of Circadian Rhythms with Random Effects and Smoothing Spline ANOVA Decompositions. Biometrics, 59:804-812.
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