tests/testthat/_snaps/t_aesi_slide.md

In autoslider.core: Slide Automation for Tables, Listings and Figures

Test table creation of t_aesi_slide (AESI summary table) with AETOXGR grading

Code
  t_aesi_slide(testdata$adsl, testdata$adae, aesi = "CQ01NAM", arm = "ACTARM")
Output
                                                                                     A: Drug X    B: Placebo    C: Combination
                                                                                      (N=134)       (N=134)        (N=132)    
  ————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
  Total number of patients with at least one AESI                                   97 (72.4%)    93 (69.4%)      99 (75.0%)  
  Total number of AESIs                                                                 396           380            465      
  Total number of patients with at least one AESI by worst grade                                                              
    Grade 1                                                                          4 (3.0%)      3 (2.2%)           0       
    Grade 2                                                                          6 (4.5%)      10 (7.5%)       7 (5.3%)   
    Grade 3                                                                         18 (13.4%)    14 (10.4%)      16 (12.1%)  
    Grade 4                                                                         15 (11.2%)    20 (14.9%)      18 (13.6%)  
    Grade 5 (fatal outcome)                                                         76 (56.7%)    70 (52.2%)      75 (56.8%)  
  Total number of patients with study drug withdrawn due to AESI                    21 (15.7%)    15 (11.2%)      26 (19.7%)  
  Total number of patients with dose modified/interrupted due to AESI               56 (41.8%)    63 (47.0%)      64 (48.5%)  
  Total number of patients with treatment received for AESI                         91 (67.9%)    93 (69.4%)      95 (72.0%)  
  Total number of patients with all non-fatal AESIs resolved                        23 (17.2%)    17 (12.7%)      19 (14.4%)  
  Total number of patients with at least one unresolved or ongoing non-fatal AESI   96 (71.6%)    100 (74.6%)     97 (73.5%)  
  Total number of patients with at least one serious AESI                           104 (77.6%)   101 (75.4%)     99 (75.0%)  
  Total number of patients with at least one related AESI                           99 (73.9%)    98 (73.1%)     102 (77.3%)

Test table creation of t_aesi_slide (AESI summary table) with AESEV grading

Code
  t_aesi_slide(testdata$adsl, testdata$adae_aesev, aesi = "CQ01NAM", arm = "ACTARM",
  grad_var = "AESEV")
Output
                                                                                     A: Drug X    B: Placebo    C: Combination
                                                                                      (N=134)       (N=134)        (N=132)    
  ————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
  Total number of patients with at least one AESI                                   97 (72.4%)    93 (69.4%)      99 (75.0%)  
  Total number of AESIs                                                                 396           380            465      
  Total number of patients with at least one AESI by worst grade                                                              
    Mild                                                                             10 (7.5%)     13 (9.7%)       7 (5.3%)   
    Moderate                                                                        18 (13.4%)    14 (10.4%)      16 (12.1%)  
    Severe                                                                          91 (67.9%)    90 (67.2%)      93 (70.5%)  
  Total number of patients with study drug withdrawn due to AESI                    21 (15.7%)    15 (11.2%)      26 (19.7%)  
  Total number of patients with dose modified/interrupted due to AESI               56 (41.8%)    63 (47.0%)      64 (48.5%)  
  Total number of patients with treatment received for AESI                         91 (67.9%)    93 (69.4%)      95 (72.0%)  
  Total number of patients with all non-fatal AESIs resolved                        23 (17.2%)    17 (12.7%)      19 (14.4%)  
  Total number of patients with at least one unresolved or ongoing non-fatal AESI   96 (71.6%)    100 (74.6%)     97 (73.5%)  
  Total number of patients with at least one serious AESI                           104 (77.6%)   101 (75.4%)     99 (75.0%)  
  Total number of patients with at least one related AESI                           99 (73.9%)    98 (73.1%)     102 (77.3%)

Test table creation of t_aesi_slide (AESI summary table) with custom AEGRP grouping

Code
  t_aesi_slide(testdata$adsl, testdata$adae_custom, aesi = "CQ01NAM", arm = "ARM",
  grad_var = "AEGRP")
Output
                                                                                     A: Drug X    B: Placebo    C: Combination
                                                                                      (N=134)       (N=134)        (N=132)    
  ————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————————
  Total number of patients with at least one AESI                                   97 (72.4%)    93 (69.4%)      99 (75.0%)  
  Total number of AESIs                                                                 396           380            465      
  Total number of patients with at least one AESI by worst grade                                                              
    Grade 1-2                                                                        10 (7.5%)     13 (9.7%)       7 (5.3%)   
    Grade 3-5                                                                       109 (81.3%)   104 (77.6%)    109 (82.6%)  
  Total number of patients with study drug withdrawn due to AESI                    21 (15.7%)    15 (11.2%)      26 (19.7%)  
  Total number of patients with dose modified/interrupted due to AESI               56 (41.8%)    63 (47.0%)      64 (48.5%)  
  Total number of patients with treatment received for AESI                         91 (67.9%)    93 (69.4%)      95 (72.0%)  
  Total number of patients with all non-fatal AESIs resolved                        23 (17.2%)    17 (12.7%)      19 (14.4%)  
  Total number of patients with at least one unresolved or ongoing non-fatal AESI   96 (71.6%)    100 (74.6%)     97 (73.5%)  
  Total number of patients with at least one serious AESI                           104 (77.6%)   101 (75.4%)     99 (75.0%)  
  Total number of patients with at least one related AESI                           99 (73.9%)    98 (73.1%)     102 (77.3%)

autoslider.core documentation built on April 4, 2025, 2:05 a.m.