ratioa | R Documentation |
Performs batch effect adjustment using Ratio-A. Here, the variable values are divided by the batch-specific arithmetic mean of the corresponding variable.
ratioa(x, batch)
x |
matrix. The covariate matrix. Observations in rows, variables in columns. |
batch |
factor. Batch variable. Each factor level (or 'category') corresponds to one of the batches. For example, if there are four batches, this variable would have four factor levels and observations with the same factor level would belong to the same batch. |
ratioa
returns an object of class ratioa
.
An object of class "ratioa
" is a list containing the following components:
xadj |
matrix of adjusted (training) data |
nbatches |
number of batches |
batch |
batch variable |
Roman Hornung
Luo, J., Schumacher, M., Scherer, A., Sanoudou, D., Megherbi, D., Davison, T., Shi, T., Tong, W., Shi, L., Hong, H., Zhao, C., Elloumi, F., Shi, W., Thomas, R., Lin, S., Tillinghast, G., Liu, G., Zhou, Y., Herman, D., Li, Y., Deng, Y., Fang, H., Bushel, P., Woods, M., Zhang, J. (2010). A comparison of batch effect removal methods for enhancement of prediction performance using maqc-ii microarray gene expression data. The Pharmacogenomics Journal 10:278-291, <doi: 10.1038/tpj.2010.57>.
data(autism) params <- ratioa(x=X, batch=batch)
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.