weights_separate: Separate Analysis in Each Basket

In baskexact: Analytical Calculation of Basket Trial Operating Characteristics

Separate Analysis in Each Basket

Description

Separate Analysis in Each Basket

Usage

weights_separate(design, ...)

## S4 method for signature 'OneStageBasket'
weights_separate(design, n, ...)

## S4 method for signature 'TwoStageBasket'
weights_separate(design, n, n1, ...)

Arguments

design	An object of class Basket created by setupOneStageBasket or setupTwoStageBasket.
...	Further arguments.
n	The sample size per basket.
n1	The sample size per basket for the interim analysis in case of a two-stage design.

Details

When weights_separate is used as a weight function, a separate analysis performed in each basket.

Value

A weight matrix where all weights are 0.

Methods (by class)

• weights_separate(OneStageBasket): Separate analysis for a single-stage basket design

• weights_separate(TwoStageBasket): Separate analysis for a two-stage basket design

Examples

design <- setupOneStageBasket(k = 3, p0 = 0.2)
toer(design, n = 15, lambda = 0.99, weight_fun = weights_separate)

baskexact documentation built on May 29, 2024, 4:39 a.m.