bisect: Estimating Cell Type Composition from Methylation Sequencing Data

An implementation of Bisect, a method for inferring cell type composition of samples based on methylation sequencing data (Whole Genome Bisulfite Sequencing and Reduced Representation Sequencing). The method is specifically tailored for sequencing data, and therefore works better than methods developed for methylation arrays. It contains a supervised mode that requires a reference (the methylation probabilities in the pure cell types), and a semi-supervised mode, that requires cell counts for a subset of the samples, but does not require a reference.

Package details

AuthorEyal Fisher [aut, cre]
MaintainerEyal Fisher <[email protected]>
LicenseGPL-3
Version0.9.0
URL https://github.com/EyalFisher/BiSect
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("bisect")

Try the bisect package in your browser

Any scripts or data that you put into this service are public.

bisect documentation built on April 16, 2018, 5:06 p.m.