GDIpathway2: GDIpathway Bayesian Networks

In bnRep: A Repository of Bayesian Networks from the Academic Literature

GDIpathway Bayesian Networks

Description

Integrative network modeling highlights the crucial roles of Rho-GDI signaling pathway in the progression of non-small cell lung cancer.

Format

A discrete Bayesian network to pinpoint key cellular factors and pathways likely to be involved with the onset and progression of non-small cell lung cancer (unhealthy patients). The network was available from an associated repository. The vertices are:

ARHGAP6

(Above, Below);

ARHGEF19

(Above, Below);

CD44

(Above, Below);

CDC42-IT1

(Above, Below);

CDH1

(Above, Below);

CFL2

(Above, Below);

DAGLB

(Above, Below);

DGKZ

(Above, Below);

DLC1

(Above, Below);

ECM1

(Above, Below);

ERMAP

(Above, Below);

ERMP1

(Above, Below);

GNA11

(Above, Below);

GNG11

(Above, Below);

GPRC5A

(Above, Below);

ITGB2

(Above, Below);

LACTB

(Above, Below);

LIMK2

(Above, Below);

PAAF1

(Above, Below);

PAK1

(Above, Below);

PAK1

(Above, Below);

PIP

(Above, Below);

PIP4K2A

(Above, Below);

PIP5K1B

(Above, Below);

RAC2

(Above, Below);

RHOJ

(Above, Below);

ROCK2

(Above, Below);

RTKN

(Above, Below);

Value

An object of class bn.fit. Refer to the documentation of bnlearn for details.

References

Gupta, S., Vundavilli, H., Osorio, R. S. A., Itoh, M. N., Mohsen, A., Datta, A., ... & Tripathi, L. P. (2022). Integrative network modeling highlights the crucial roles of rho-GDI signaling pathway in the progression of non-small cell lung cancer. IEEE Journal of Biomedical and Health Informatics, 26(9), 4785-4793.

bnRep documentation built on April 12, 2025, 1:13 a.m.