braidReports-package: Visualize Combined Action Response Surfaces and Report BRAID...

In braidReports: Visualize Combined Action Response Surfaces and Report BRAID Analyses

Description

Building on the ggplot2 plotting package, this package provides functions to generate, format, and style surface plots for visualizing combined action data without resorting to three-dimensional surface plots, which can be difficult to interpret. The package also provides functions for reporting on a BRAID analysis, including plotting curve-shifts, calculating IAE values, and producing full BRAID analysis reports.

Details

Package:	braidReports
Type:	Package
Version:	0.5.3
Date:	2016-04-05
License:	GPL (>=3)

The heart of the package is the function responseMap, which produces a ggplot2 tile or surface plot from combined action data, consolidating many of the minutiae of plotting such surfaces into a single, easily used function. The functions formatResponseMap and formatDifferenceMap provide pre-built formatting and themes for quickly generating publishable or shareable activity plots and error plots. In addition, several functions provide additional analytical and reporting options for BRAID analyses (from the package braidrm). The function calculateIAE estimates the combined therapeutic window for a pair of active compounds; the function potentiationPlot produces fast and easy curve-shift plots to visualize the potentiation of one compound by the presence of another; and makeBRAIDreport serves as a (nearly) fully-functional apparatus for translating a BRAID analysis into a one-page comprehensive report.

Author(s)

Nathaniel R. Twarog <[e-mail]>

References

Twarog, N.R., Stewart, E., Vowell Hamill, C., and Shelat, A. BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action. Scientific Reports In Press (2016).

See Also

braidrm-package

braidReports documentation built on Jan. 6, 2021, 1:06 a.m.