cardioModel: Cardiovascular Safety Exposure-Response Modeling in Early-Phase Clinical Studies

Includes over 100 mixed-effects model structures describing the relationship between drug concentration and QT interval, heart rate/pulse rate or blood pressure. Given an exposure-response dataset, the tool fits each model structure to the observed data.

Install the latest version of this package by entering the following in R:
AuthorDaniela J Conrado [aut, cre], Gregory J Hather [aut], William S Denney [aut], Danny Chen [ctb]
Date of publication2016-04-04 08:06:43
MaintainerDaniela J Conrado <>

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