cardioModel: Cardiovascular Safety Exposure-Response Modeling in Early-Phase Clinical Studies

Includes over 100 mixed-effects model structures describing the relationship between drug concentration and QT interval, heart rate/pulse rate or blood pressure. Given an exposure-response dataset, the tool fits each model structure to the observed data.

Getting started

Package details

AuthorDaniela J Conrado [aut, cre], Gregory J Hather [aut], William S Denney [aut], Danny Chen [ctb]
MaintainerDaniela J Conrado <[email protected]>
Package repositoryView on CRAN
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cardioModel documentation built on May 2, 2019, 5:16 a.m.