Functions to fit cell volume distributions and thereby estimate cell growth rates and division times

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Description

This package implements a methodology for using cell volume distributions to estimate cell growth rates and division times that is described in the paper entitled "Cell Volume Distributions Reveal Cell Growth Rates and Division Times", by Michael Halter, John T. Elliott, Joseph B. Hubbard, Alessandro Tona and Anne L. Plant, which is in press in the Journal of Theoretical Biology. In order to reproduce the analysis used to obtain Table 1 in the paper, execute the command example(fitVolDist).

Details

The package fits a model for cell volume distributions under least squares criteria using the function nls.lm. Estimates for cell growth rate and division time are thereby obtained.

References

Halter M, Elliott JT, Hubbard JB, Tona A, Plant AL (2009), "Cell Volume Distributions Reveal Cell Growth Rates and Division Times.", Journal of Theoretical Biology, in press.

See Also

nls.lm