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tests/testthat/_snaps/cfbt01.md
In chevron: Standard TLGs for Clinical Trials Reporting
cfbt01 functions with default argument value return expected result with test data
Code
cat(export_as_txt(res, lpp = 100))
Output
Parameter: Diastolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.385 (17.067) NE (NE) 106.381 (20.586) NE (NE)
Median 94.933 NE 111.133 NE
Min - Max 55.71 - 122.00 NE - NE 60.21 - 131.91 NE - NE
BASELINE
n 15 15
Mean (SD) 96.133 (22.458) 108.111 (15.074)
Median 93.328 108.951
Min - Max 60.58 - 136.59 83.44 - 131.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 98.977 (21.359) 2.844 (28.106) 104.110 (16.172) -4.001 (21.867)
Median 92.447 -4.066 107.703 3.227
Min - Max 67.55 - 130.37 -32.82 - 47.68 70.91 - 132.89 -52.94 - 28.63
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.758 (14.477) 3.626 (21.189) 97.473 (17.296) -10.638 (20.831)
Median 101.498 1.731 99.501 -9.727
Min - Max 71.98 - 122.81 -39.50 - 47.57 53.80 - 125.81 -55.15 - 25.26
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.101 (26.109) 2.968 (34.327) 91.984 (16.925) -16.127 (21.881)
Median 101.146 -0.271 91.244 -14.384
Min - Max 47.68 - 162.22 -47.87 - 76.64 67.80 - 119.72 -53.06 - 22.52
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.400 (22.273) 7.267 (30.740) 96.467 (19.451) -11.644 (25.922)
Median 98.168 2.510 97.385 -16.793
Min - Max 63.09 - 148.25 -38.43 - 61.90 63.35 - 131.57 -57.11 - 48.13
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.222 (18.536) -2.911 (28.873) 97.890 (20.701) -10.221 (27.593)
Median 90.799 -3.385 99.049 -11.319
Min - Max 63.55 - 139.11 -48.63 - 47.35 69.47 - 137.64 -54.38 - 37.85
\s\n
Parameter: Diastolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.468 (12.628) NE (NE)
Median 108.359 NE
Min - Max 83.29 - 127.17 NE - NE
BASELINE
n 15
Mean (SD) 103.149 (19.752)
Median 102.849
Min - Max 66.05 - 136.55
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.826 (19.027) -2.323 (25.018)
Median 103.058 -2.476
Min - Max 70.04 - 128.68 -55.15 - 41.81
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.272 (16.961) -8.877 (27.229)
Median 96.789 -10.155
Min - Max 63.45 - 117.47 -73.10 - 46.54
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.586 (13.560) -8.563 (21.713)
Median 98.398 -16.075
Min - Max 73.50 - 115.43 -37.90 - 32.66
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.338 (18.417) 5.189 (21.881)
Median 107.555 7.966
Min - Max 68.78 - 132.52 -33.96 - 41.50
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.317 (16.401) -7.832 (19.827)
Median 93.876 -4.665
Min - Max 71.91 - 138.54 -44.47 - 29.11
\s\n
Parameter: Pulse Rate
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 79.848 (13.356) NE (NE) 82.170 (18.331) NE (NE)
Median 78.706 NE 78.554 NE
Min - Max 48.94 - 102.62 NE - NE 55.11 - 122.56 NE - NE
BASELINE
n 15 15
Mean (SD) 81.896 (10.297) 85.584 (14.663)
Median 81.733 80.261
Min - Max 62.38 - 102.46 63.62 - 115.60
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 73.932 (16.268) -7.963 (15.197) 81.615 (15.744) -3.969 (19.689)
Median 77.008 -7.885 82.358 -0.486
Min - Max 37.37 - 97.36 -35.04 - 21.67 53.97 - 102.01 -61.63 - 26.24
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 77.164 (14.067) -4.731 (19.872) 80.645 (7.774) -4.939 (17.465)
Median 80.424 -7.412 80.107 -9.642
Min - Max 51.40 - 102.39 -40.41 - 36.25 66.90 - 92.92 -38.18 - 20.90
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 83.812 (12.679) 1.916 (16.213) 83.354 (18.590) -2.230 (19.940)
Median 87.736 2.160 86.412 3.513
Min - Max 46.95 - 102.74 -28.74 - 25.43 43.66 - 107.29 -29.19 - 43.67
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 74.829 (12.786) -7.067 (16.097) 79.151 (12.081) -6.433 (17.236)
Median 76.227 -5.506 78.650 -8.084
Min - Max 48.95 - 95.54 -38.03 - 13.57 54.79 - 105.87 -35.78 - 25.73
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 79.792 (11.206) -2.104 (13.269) 87.561 (17.865) 1.977 (19.814)
Median 82.997 -0.210 82.023 3.049
Min - Max 55.68 - 92.89 -24.05 - 20.22 65.33 - 128.99 -50.27 - 32.78
\s\n
Parameter: Pulse Rate
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 79.679 (15.350) NE (NE)
Median 76.903 NE
Min - Max 59.79 - 110.03 NE - NE
BASELINE
n 15
Mean (SD) 77.107 (14.159)
Median 78.950
Min - Max 52.36 - 96.61
WEEK 1 DAY 8
n 15 15
Mean (SD) 76.625 (15.814) -0.482 (20.797)
Median 79.731 8.488
Min - Max 48.84 - 104.77 -37.33 - 28.64
WEEK 2 DAY 15
n 15 15
Mean (SD) 79.044 (13.193) 1.937 (15.609)
Median 74.361 5.695
Min - Max 65.32 - 111.55 -22.38 - 27.05
WEEK 3 DAY 22
n 15 15
Mean (SD) 75.924 (10.045) -1.183 (16.167)
Median 74.720 0.057
Min - Max 61.17 - 95.54 -27.66 - 27.57
WEEK 4 DAY 29
n 15 15
Mean (SD) 77.979 (14.535) 0.872 (20.465)
Median 78.231 2.808
Min - Max 51.48 - 104.71 -33.19 - 44.14
WEEK 5 DAY 36
n 15 15
Mean (SD) 84.617 (17.937) 7.510 (21.612)
Median 84.022 12.943
Min - Max 34.86 - 110.03 -42.18 - 41.69
\s\n
Parameter: Respiratory Rate
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 15.043 (3.455) NE (NE) 16.400 (3.741) NE (NE)
Median 15.743 NE 16.303 NE
Min - Max 5.75 - 20.24 NE - NE 9.79 - 25.68 NE - NE
BASELINE
n 15 15
Mean (SD) 13.353 (5.061) 16.270 (5.086)
Median 13.202 15.898
Min - Max 4.68 - 23.59 9.51 - 25.27
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 15.832 (5.336) 2.478 (6.550) 14.301 (4.143) -1.969 (6.549)
Median 13.364 3.245 13.556 -0.768
Min - Max 7.24 - 24.69 -12.99 - 14.74 7.80 - 21.64 -14.50 - 8.50
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 15.195 (5.532) 1.842 (6.646) 16.335 (6.402) 0.065 (8.770)
Median 15.137 3.348 15.710 0.144
Min - Max 2.50 - 24.34 -15.54 - 9.87 8.02 - 26.40 -17.25 - 14.68
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 12.757 (6.587) -0.597 (5.529) 16.806 (5.518) 0.537 (8.174)
Median 11.334 1.128 17.496 -0.116
Min - Max 0.62 - 22.74 -12.26 - 5.99 6.06 - 26.22 -17.50 - 11.77
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 14.950 (4.443) 1.597 (4.795) 14.464 (4.510) -1.805 (6.965)
Median 15.727 2.893 13.246 -0.655
Min - Max 7.98 - 21.41 -8.31 - 7.94 5.60 - 20.66 -14.26 - 11.00
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 13.632 (6.374) 0.279 (8.063) 19.383 (5.590) 3.113 (6.914)
Median 13.068 0.442 18.527 1.760
Min - Max 2.34 - 24.54 -17.58 - 9.42 11.62 - 28.62 -6.74 - 18.02
\s\n
Parameter: Respiratory Rate
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 15.781 (4.800) NE (NE)
Median 16.645 NE
Min - Max 7.32 - 21.56 NE - NE
BASELINE
n 15
Mean (SD) 15.339 (3.052)
Median 15.491
Min - Max 10.90 - 20.89
WEEK 1 DAY 8
n 15 15
Mean (SD) 14.673 (6.117) -0.666 (7.274)
Median 16.835 2.369
Min - Max 1.65 - 20.89 -15.56 - 8.01
WEEK 2 DAY 15
n 15 15
Mean (SD) 16.777 (5.546) 1.439 (5.186)
Median 17.770 1.783
Min - Max 2.57 - 22.56 -10.09 - 9.60
WEEK 3 DAY 22
n 15 15
Mean (SD) 14.975 (5.562) -0.364 (6.029)
Median 15.340 -0.615
Min - Max 4.81 - 22.60 -10.55 - 10.78
WEEK 4 DAY 29
n 15 15
Mean (SD) 14.016 (8.365) -1.323 (9.534)
Median 15.704 0.213
Min - Max 1.00 - 27.54 -14.36 - 13.97
WEEK 5 DAY 36
n 15 15
Mean (SD) 15.623 (5.417) 0.284 (7.141)
Median 15.202 -0.157
Min - Max 4.46 - 29.18 -11.90 - 13.69
\s\n
Parameter: Systolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.073 (33.511) NE (NE) 157.840 (34.393) NE (NE)
Median 156.169 NE 161.670 NE
Min - Max 78.31 - 210.70 NE - NE 79.76 - 210.40 NE - NE
BASELINE
n 15 15
Mean (SD) 145.925 (28.231) 152.007 (28.664)
Median 142.705 157.698
Min - Max 85.21 - 195.68 98.90 - 194.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.509 (21.097) 10.584 (34.598) 147.480 (33.473) -4.527 (48.895)
Median 160.711 5.802 155.030 2.758
Min - Max 126.84 - 185.53 -53.28 - 91.52 85.22 - 189.88 -77.34 - 90.98
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.202 (33.676) -1.723 (27.067) 136.892 (30.178) -15.115 (37.794)
Median 144.253 5.325 142.679 -14.083
Min - Max 62.56 - 203.66 -53.89 - 44.16 70.34 - 174.27 -83.07 - 62.39
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.887 (35.374) 8.962 (38.455) 149.761 (28.944) -2.247 (44.835)
Median 158.938 17.191 155.044 -1.796
Min - Max 112.32 - 218.83 -47.28 - 96.18 84.42 - 192.92 -110.20 - 94.02
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.159 (32.249) 4.234 (32.965) 156.043 (22.863) 4.036 (42.494)
Median 145.506 3.754 149.094 -10.000
Min - Max 69.37 - 210.43 -89.16 - 54.32 113.57 - 195.10 -71.44 - 77.75
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 155.964 (30.945) 10.039 (42.252) 156.387 (35.274) 4.380 (51.782)
Median 158.142 1.448 164.552 7.060
Min - Max 110.61 - 212.47 -53.91 - 90.45 63.28 - 198.79 -131.34 - 86.84
\s\n
Parameter: Systolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.407 (22.311) NE (NE)
Median 149.556 NE
Min - Max 108.21 - 184.88 NE - NE
BASELINE
n 15
Mean (SD) 154.173 (26.317)
Median 155.282
Min - Max 86.65 - 192.68
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.319 (30.759) -10.854 (34.553)
Median 145.548 -5.636
Min - Max 90.37 - 191.58 -65.71 - 49.04
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.622 (27.088) -5.551 (44.670)
Median 147.102 -11.512
Min - Max 108.82 - 200.23 -69.54 - 113.59
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.460 (21.352) -3.712 (37.984)
Median 156.505 -7.606
Min - Max 94.70 - 180.41 -74.91 - 72.74
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.714 (22.980) -8.458 (33.175)
Median 150.797 -14.432
Min - Max 106.91 - 188.09 -41.95 - 65.16
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.592 (33.170) -10.581 (44.799)
Median 148.501 -2.385
Min - Max 92.18 - 191.05 -78.77 - 64.35
\s\n
Parameter: Temperature
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 36.273 (1.136) NE (NE) 36.731 (1.142) NE (NE)
Median 36.131 NE 36.506 NE
Min - Max 34.07 - 38.59 NE - NE 34.97 - 39.04 NE - NE
BASELINE
n 15 15
Mean (SD) 36.763 (1.167) 36.707 (1.528)
Median 36.694 37.144
Min - Max 35.08 - 38.72 33.65 - 38.92
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 36.280 (0.543) -0.483 (1.022) 36.292 (1.378) -0.415 (1.957)
Median 36.194 -0.609 36.451 -0.344
Min - Max 35.37 - 37.06 -2.07 - 1.11 33.03 - 38.47 -4.72 - 2.24
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 37.090 (1.136) 0.328 (1.647) 36.577 (1.291) -0.130 (1.799)
Median 37.138 0.153 36.113 0.300
Min - Max 34.44 - 38.95 -2.34 - 2.85 34.86 - 39.29 -3.52 - 2.55
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 36.725 (1.003) -0.038 (1.441) 36.546 (1.008) -0.161 (1.701)
Median 36.616 0.029 36.378 -0.368
Min - Max 35.24 - 38.26 -3.25 - 2.34 35.08 - 38.17 -2.59 - 4.13
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 36.545 (1.070) -0.218 (1.859) 36.574 (1.024) -0.133 (1.994)
Median 36.299 -0.701 36.546 -0.436
Min - Max 34.87 - 39.00 -3.85 - 3.10 34.77 - 38.98 -2.74 - 4.07
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 37.038 (0.918) 0.275 (1.334) 36.823 (1.247) 0.117 (1.387)
Median 36.945 0.346 36.839 -0.476
Min - Max 35.71 - 38.45 -2.78 - 2.77 34.69 - 38.91 -1.76 - 3.06
\s\n
Parameter: Temperature
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 36.565 (1.112) NE (NE)
Median 36.681 NE
Min - Max 35.30 - 38.90 NE - NE
BASELINE
n 15
Mean (SD) 36.383 (0.963)
Median 36.496
Min - Max 34.71 - 37.92
WEEK 1 DAY 8
n 15 15
Mean (SD) 36.848 (0.936) 0.465 (1.458)
Median 36.973 0.399
Min - Max 35.28 - 38.18 -1.44 - 2.99
WEEK 2 DAY 15
n 15 15
Mean (SD) 36.620 (1.077) 0.237 (1.595)
Median 36.519 0.690
Min - Max 34.89 - 38.33 -3.02 - 2.47
WEEK 3 DAY 22
n 15 15
Mean (SD) 36.697 (0.694) 0.314 (1.312)
Median 36.679 0.841
Min - Max 35.14 - 37.64 -2.77 - 2.63
WEEK 4 DAY 29
n 15 15
Mean (SD) 36.738 (0.760) 0.355 (0.872)
Median 36.585 0.352
Min - Max 35.29 - 38.24 -0.91 - 2.14
WEEK 5 DAY 36
n 15 15
Mean (SD) 36.716 (1.056) 0.333 (1.344)
Median 36.404 0.500
Min - Max 35.26 - 38.64 -1.83 - 3.72
\s\n
Parameter: Weight
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 81.827 (23.644) NE (NE) 61.563 (19.272) NE (NE)
Median 80.182 NE 62.147 NE
Min - Max 40.48 - 133.35 NE - NE 23.27 - 92.39 NE - NE
BASELINE
n 15 15
Mean (SD) 76.532 (15.588) 70.870 (12.845)
Median 71.929 66.405
Min - Max 56.24 - 102.43 54.36 - 96.85
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 71.171 (19.805) -5.360 (23.082) 69.872 (17.781) -0.998 (20.176)
Median 65.106 -6.780 70.971 -2.628
Min - Max 47.03 - 123.95 -49.07 - 40.63 30.55 - 93.75 -35.86 - 28.87
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 80.484 (18.937) 3.952 (22.123) 72.940 (20.302) 2.070 (17.837)
Median 75.792 3.284 71.374 3.396
Min - Max 44.83 - 112.37 -36.68 - 35.07 35.00 - 106.69 -32.41 - 26.17
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 68.100 (15.095) -8.431 (18.100) 71.883 (18.376) 1.013 (22.760)
Median 66.175 -7.353 76.267 3.928
Min - Max 30.53 - 91.08 -46.15 - 29.48 20.87 - 95.04 -43.57 - 29.54
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 73.294 (18.861) -3.238 (18.094) 71.553 (17.090) 0.683 (16.404)
Median 76.829 -0.941 70.705 -1.527
Min - Max 24.32 - 98.14 -44.46 - 18.39 43.61 - 107.47 -26.14 - 43.89
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 66.719 (15.750) -9.812 (26.403) 68.162 (15.787) -2.708 (20.179)
Median 64.046 -5.370 67.480 -1.537
Min - Max 33.02 - 95.14 -69.42 - 26.72 45.71 - 102.63 -36.52 - 30.47
\s\n
Parameter: Weight
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 64.923 (16.678) NE (NE)
Median 62.745 NE
Min - Max 26.70 - 94.66 NE - NE
BASELINE
n 15
Mean (SD) 71.676 (16.922)
Median 68.883
Min - Max 27.15 - 107.89
WEEK 1 DAY 8
n 15 15
Mean (SD) 74.799 (13.706) 3.123 (21.964)
Median 71.374 4.336
Min - Max 53.19 - 96.54 -32.10 - 51.00
WEEK 2 DAY 15
n 15 15
Mean (SD) 67.267 (19.187) -4.409 (25.986)
Median 60.651 -5.246
Min - Max 35.56 - 102.05 -67.52 - 33.50
WEEK 3 DAY 22
n 15 15
Mean (SD) 70.442 (21.914) -1.234 (25.307)
Median 72.649 5.691
Min - Max 31.36 - 101.13 -45.69 - 32.28
WEEK 4 DAY 29
n 15 15
Mean (SD) 77.447 (21.174) 5.771 (25.479)
Median 86.161 19.614
Min - Max 41.60 - 112.40 -40.90 - 35.30
WEEK 5 DAY 36
n 15 15
Mean (SD) 65.688 (23.847) -5.988 (35.176)
Median 71.788 -7.456
Min - Max 12.04 - 114.55 -71.68 - 87.41
cfbt01 can handle n = 0 and outputs NE instead of infs and NAs
Code
cat(export_as_txt(res, lpp = 100))
Output
Parameter: Diastolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.385 (17.067) NE (NE) 106.381 (20.586) NE (NE)
Median 94.933 NE 111.133 NE
Min - Max 55.71 - 122.00 NE - NE 60.21 - 131.91 NE - NE
BASELINE
n 15 15
Mean (SD) 96.133 (22.458) 108.111 (15.074)
Median 93.328 108.951
Min - Max 60.58 - 136.59 83.44 - 131.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 98.977 (21.359) 2.844 (28.106) 104.110 (16.172) -4.001 (21.867)
Median 92.447 -4.066 107.703 3.227
Min - Max 67.55 - 130.37 -32.82 - 47.68 70.91 - 132.89 -52.94 - 28.63
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.758 (14.477) 3.626 (21.189) 97.473 (17.296) -10.638 (20.831)
Median 101.498 1.731 99.501 -9.727
Min - Max 71.98 - 122.81 -39.50 - 47.57 53.80 - 125.81 -55.15 - 25.26
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.101 (26.109) 2.968 (34.327) 91.984 (16.925) -16.127 (21.881)
Median 101.146 -0.271 91.244 -14.384
Min - Max 47.68 - 162.22 -47.87 - 76.64 67.80 - 119.72 -53.06 - 22.52
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.400 (22.273) 7.267 (30.740) 96.467 (19.451) -11.644 (25.922)
Median 98.168 2.510 97.385 -16.793
Min - Max 63.09 - 148.25 -38.43 - 61.90 63.35 - 131.57 -57.11 - 48.13
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.222 (18.536) -2.911 (28.873) 97.890 (20.701) -10.221 (27.593)
Median 90.799 -3.385 99.049 -11.319
Min - Max 63.55 - 139.11 -48.63 - 47.35 69.47 - 137.64 -54.38 - 37.85
\s\n
Parameter: Diastolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.468 (12.628) NE (NE)
Median 108.359 NE
Min - Max 83.29 - 127.17 NE - NE
BASELINE
n 15
Mean (SD) 103.149 (19.752)
Median 102.849
Min - Max 66.05 - 136.55
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.826 (19.027) -2.323 (25.018)
Median 103.058 -2.476
Min - Max 70.04 - 128.68 -55.15 - 41.81
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.272 (16.961) -8.877 (27.229)
Median 96.789 -10.155
Min - Max 63.45 - 117.47 -73.10 - 46.54
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.586 (13.560) -8.563 (21.713)
Median 98.398 -16.075
Min - Max 73.50 - 115.43 -37.90 - 32.66
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.338 (18.417) 5.189 (21.881)
Median 107.555 7.966
Min - Max 68.78 - 132.52 -33.96 - 41.50
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.317 (16.401) -7.832 (19.827)
Median 93.876 -4.665
Min - Max 71.91 - 138.54 -44.47 - 29.11
\s\n
Parameter: Systolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.073 (33.511) NE (NE) 157.840 (34.393) NE (NE)
Median 156.169 NE 161.670 NE
Min - Max 78.31 - 210.70 NE - NE 79.76 - 210.40 NE - NE
BASELINE
n 15 15
Mean (SD) 145.925 (28.231) 152.007 (28.664)
Median 142.705 157.698
Min - Max 85.21 - 195.68 98.90 - 194.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.509 (21.097) 10.584 (34.598) 147.480 (33.473) -4.527 (48.895)
Median 160.711 5.802 155.030 2.758
Min - Max 126.84 - 185.53 -53.28 - 91.52 85.22 - 189.88 -77.34 - 90.98
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.202 (33.676) -1.723 (27.067) 136.892 (30.178) -15.115 (37.794)
Median 144.253 5.325 142.679 -14.083
Min - Max 62.56 - 203.66 -53.89 - 44.16 70.34 - 174.27 -83.07 - 62.39
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.887 (35.374) 8.962 (38.455) 149.761 (28.944) -2.247 (44.835)
Median 158.938 17.191 155.044 -1.796
Min - Max 112.32 - 218.83 -47.28 - 96.18 84.42 - 192.92 -110.20 - 94.02
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.159 (32.249) 4.234 (32.965) 156.043 (22.863) 4.036 (42.494)
Median 145.506 3.754 149.094 -10.000
Min - Max 69.37 - 210.43 -89.16 - 54.32 113.57 - 195.10 -71.44 - 77.75
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 155.964 (30.945) 10.039 (42.252) 156.387 (35.274) 4.380 (51.782)
Median 158.142 1.448 164.552 7.060
Min - Max 110.61 - 212.47 -53.91 - 90.45 63.28 - 198.79 -131.34 - 86.84
\s\n
Parameter: Systolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.407 (22.311) NE (NE)
Median 149.556 NE
Min - Max 108.21 - 184.88 NE - NE
BASELINE
n 15
Mean (SD) 154.173 (26.317)
Median 155.282
Min - Max 86.65 - 192.68
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.319 (30.759) -10.854 (34.553)
Median 145.548 -5.636
Min - Max 90.37 - 191.58 -65.71 - 49.04
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.622 (27.088) -5.551 (44.670)
Median 147.102 -11.512
Min - Max 108.82 - 200.23 -69.54 - 113.59
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.460 (21.352) -3.712 (37.984)
Median 156.505 -7.606
Min - Max 94.70 - 180.41 -74.91 - 72.74
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.714 (22.980) -8.458 (33.175)
Median 150.797 -14.432
Min - Max 106.91 - 188.09 -41.95 - 65.16
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.592 (33.170) -10.581 (44.799)
Median 148.501 -2.385
Min - Max 92.18 - 191.05 -78.77 - 64.35
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Code
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Output
Parameter: Diastolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.385 (17.067) NE (NE) 106.381 (20.586) NE (NE)
Median 94.933 NE 111.133 NE
Min - Max 55.71 - 122.00 NE - NE 60.21 - 131.91 NE - NE
BASELINE
n 15 15
Mean (SD) 96.133 (22.458) 108.111 (15.074)
Median 93.328 108.951
Min - Max 60.58 - 136.59 83.44 - 131.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 98.977 (21.359) 2.844 (28.106) 104.110 (16.172) -4.001 (21.867)
Median 92.447 -4.066 107.703 3.227
Min - Max 67.55 - 130.37 -32.82 - 47.68 70.91 - 132.89 -52.94 - 28.63
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.758 (14.477) 3.626 (21.189) 97.473 (17.296) -10.638 (20.831)
Median 101.498 1.731 99.501 -9.727
Min - Max 71.98 - 122.81 -39.50 - 47.57 53.80 - 125.81 -55.15 - 25.26
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.101 (26.109) 2.968 (34.327) 91.984 (16.925) -16.127 (21.881)
Median 101.146 -0.271 91.244 -14.384
Min - Max 47.68 - 162.22 -47.87 - 76.64 67.80 - 119.72 -53.06 - 22.52
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.400 (22.273) 7.267 (30.740) 96.467 (19.451) -11.644 (25.922)
Median 98.168 2.510 97.385 -16.793
Min - Max 63.09 - 148.25 -38.43 - 61.90 63.35 - 131.57 -57.11 - 48.13
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.222 (18.536) -2.911 (28.873) 97.890 (20.701) -10.221 (27.593)
Median 90.799 -3.385 99.049 -11.319
Min - Max 63.55 - 139.11 -48.63 - 47.35 69.47 - 137.64 -54.38 - 37.85
\s\n
Parameter: Diastolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.468 (12.628) NE (NE)
Median 108.359 NE
Min - Max 83.29 - 127.17 NE - NE
BASELINE
n 15
Mean (SD) 103.149 (19.752)
Median 102.849
Min - Max 66.05 - 136.55
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.826 (19.027) -2.323 (25.018)
Median 103.058 -2.476
Min - Max 70.04 - 128.68 -55.15 - 41.81
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.272 (16.961) -8.877 (27.229)
Median 96.789 -10.155
Min - Max 63.45 - 117.47 -73.10 - 46.54
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.586 (13.560) -8.563 (21.713)
Median 98.398 -16.075
Min - Max 73.50 - 115.43 -37.90 - 32.66
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.338 (18.417) 5.189 (21.881)
Median 107.555 7.966
Min - Max 68.78 - 132.52 -33.96 - 41.50
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.317 (16.401) -7.832 (19.827)
Median 93.876 -4.665
Min - Max 71.91 - 138.54 -44.47 - 29.11
\s\n
Parameter: Pulse Rate
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 79.848 (13.356) NE (NE) 82.170 (18.331) NE (NE)
Median 78.706 NE 78.554 NE
Min - Max 48.94 - 102.62 NE - NE 55.11 - 122.56 NE - NE
BASELINE
n 15 15
Mean (SD) 81.896 (10.297) 85.584 (14.663)
Median 81.733 80.261
Min - Max 62.38 - 102.46 63.62 - 115.60
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 73.932 (16.268) -7.963 (15.197) 81.615 (15.744) -3.969 (19.689)
Median 77.008 -7.885 82.358 -0.486
Min - Max 37.37 - 97.36 -35.04 - 21.67 53.97 - 102.01 -61.63 - 26.24
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 77.164 (14.067) -4.731 (19.872) 80.645 (7.774) -4.939 (17.465)
Median 80.424 -7.412 80.107 -9.642
Min - Max 51.40 - 102.39 -40.41 - 36.25 66.90 - 92.92 -38.18 - 20.90
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 83.812 (12.679) 1.916 (16.213) 83.354 (18.590) -2.230 (19.940)
Median 87.736 2.160 86.412 3.513
Min - Max 46.95 - 102.74 -28.74 - 25.43 43.66 - 107.29 -29.19 - 43.67
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 74.829 (12.786) -7.067 (16.097) 79.151 (12.081) -6.433 (17.236)
Median 76.227 -5.506 78.650 -8.084
Min - Max 48.95 - 95.54 -38.03 - 13.57 54.79 - 105.87 -35.78 - 25.73
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 79.792 (11.206) -2.104 (13.269) 87.561 (17.865) 1.977 (19.814)
Median 82.997 -0.210 82.023 3.049
Min - Max 55.68 - 92.89 -24.05 - 20.22 65.33 - 128.99 -50.27 - 32.78
\s\n
Parameter: Pulse Rate
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 79.679 (15.350) NE (NE)
Median 76.903 NE
Min - Max 59.79 - 110.03 NE - NE
BASELINE
n 15
Mean (SD) 77.107 (14.159)
Median 78.950
Min - Max 52.36 - 96.61
WEEK 1 DAY 8
n 15 15
Mean (SD) 76.625 (15.814) -0.482 (20.797)
Median 79.731 8.488
Min - Max 48.84 - 104.77 -37.33 - 28.64
WEEK 2 DAY 15
n 15 15
Mean (SD) 79.044 (13.193) 1.937 (15.609)
Median 74.361 5.695
Min - Max 65.32 - 111.55 -22.38 - 27.05
WEEK 3 DAY 22
n 15 15
Mean (SD) 75.924 (10.045) -1.183 (16.167)
Median 74.720 0.057
Min - Max 61.17 - 95.54 -27.66 - 27.57
WEEK 4 DAY 29
n 15 15
Mean (SD) 77.979 (14.535) 0.872 (20.465)
Median 78.231 2.808
Min - Max 51.48 - 104.71 -33.19 - 44.14
WEEK 5 DAY 36
n 15 15
Mean (SD) 84.617 (17.937) 7.510 (21.612)
Median 84.022 12.943
Min - Max 34.86 - 110.03 -42.18 - 41.69
\s\n
Parameter: Respiratory Rate
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 15.043 (3.455) NE (NE) 16.400 (3.741) NE (NE)
Median 15.743 NE 16.303 NE
Min - Max 5.75 - 20.24 NE - NE 9.79 - 25.68 NE - NE
BASELINE
n 15 15
Mean (SD) 13.353 (5.061) 16.270 (5.086)
Median 13.202 15.898
Min - Max 4.68 - 23.59 9.51 - 25.27
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 15.832 (5.336) 2.478 (6.550) 14.301 (4.143) -1.969 (6.549)
Median 13.364 3.245 13.556 -0.768
Min - Max 7.24 - 24.69 -12.99 - 14.74 7.80 - 21.64 -14.50 - 8.50
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 15.195 (5.532) 1.842 (6.646) 16.335 (6.402) 0.065 (8.770)
Median 15.137 3.348 15.710 0.144
Min - Max 2.50 - 24.34 -15.54 - 9.87 8.02 - 26.40 -17.25 - 14.68
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 12.757 (6.587) -0.597 (5.529) 16.806 (5.518) 0.537 (8.174)
Median 11.334 1.128 17.496 -0.116
Min - Max 0.62 - 22.74 -12.26 - 5.99 6.06 - 26.22 -17.50 - 11.77
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 14.950 (4.443) 1.597 (4.795) 14.464 (4.510) -1.805 (6.965)
Median 15.727 2.893 13.246 -0.655
Min - Max 7.98 - 21.41 -8.31 - 7.94 5.60 - 20.66 -14.26 - 11.00
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 13.632 (6.374) 0.279 (8.063) 19.383 (5.590) 3.113 (6.914)
Median 13.068 0.442 18.527 1.760
Min - Max 2.34 - 24.54 -17.58 - 9.42 11.62 - 28.62 -6.74 - 18.02
\s\n
Parameter: Respiratory Rate
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 15.781 (4.800) NE (NE)
Median 16.645 NE
Min - Max 7.32 - 21.56 NE - NE
BASELINE
n 15
Mean (SD) 15.339 (3.052)
Median 15.491
Min - Max 10.90 - 20.89
WEEK 1 DAY 8
n 15 15
Mean (SD) 14.673 (6.117) -0.666 (7.274)
Median 16.835 2.369
Min - Max 1.65 - 20.89 -15.56 - 8.01
WEEK 2 DAY 15
n 15 15
Mean (SD) 16.777 (5.546) 1.439 (5.186)
Median 17.770 1.783
Min - Max 2.57 - 22.56 -10.09 - 9.60
WEEK 3 DAY 22
n 15 15
Mean (SD) 14.975 (5.562) -0.364 (6.029)
Median 15.340 -0.615
Min - Max 4.81 - 22.60 -10.55 - 10.78
WEEK 4 DAY 29
n 15 15
Mean (SD) 14.016 (8.365) -1.323 (9.534)
Median 15.704 0.213
Min - Max 1.00 - 27.54 -14.36 - 13.97
WEEK 5 DAY 36
n 15 15
Mean (SD) 15.623 (5.417) 0.284 (7.141)
Median 15.202 -0.157
Min - Max 4.46 - 29.18 -11.90 - 13.69
\s\n
Parameter: Systolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.073 (33.511) NE (NE) 157.840 (34.393) NE (NE)
Median 156.169 NE 161.670 NE
Min - Max 78.31 - 210.70 NE - NE 79.76 - 210.40 NE - NE
BASELINE
n 15 15
Mean (SD) 145.925 (28.231) 152.007 (28.664)
Median 142.705 157.698
Min - Max 85.21 - 195.68 98.90 - 194.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.509 (21.097) 10.584 (34.598) 147.480 (33.473) -4.527 (48.895)
Median 160.711 5.802 155.030 2.758
Min - Max 126.84 - 185.53 -53.28 - 91.52 85.22 - 189.88 -77.34 - 90.98
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.202 (33.676) -1.723 (27.067) 136.892 (30.178) -15.115 (37.794)
Median 144.253 5.325 142.679 -14.083
Min - Max 62.56 - 203.66 -53.89 - 44.16 70.34 - 174.27 -83.07 - 62.39
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.887 (35.374) 8.962 (38.455) 149.761 (28.944) -2.247 (44.835)
Median 158.938 17.191 155.044 -1.796
Min - Max 112.32 - 218.83 -47.28 - 96.18 84.42 - 192.92 -110.20 - 94.02
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.159 (32.249) 4.234 (32.965) 156.043 (22.863) 4.036 (42.494)
Median 145.506 3.754 149.094 -10.000
Min - Max 69.37 - 210.43 -89.16 - 54.32 113.57 - 195.10 -71.44 - 77.75
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 155.964 (30.945) 10.039 (42.252) 156.387 (35.274) 4.380 (51.782)
Median 158.142 1.448 164.552 7.060
Min - Max 110.61 - 212.47 -53.91 - 90.45 63.28 - 198.79 -131.34 - 86.84
\s\n
Parameter: Systolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.407 (22.311) NE (NE)
Median 149.556 NE
Min - Max 108.21 - 184.88 NE - NE
BASELINE
n 15
Mean (SD) 154.173 (26.317)
Median 155.282
Min - Max 86.65 - 192.68
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.319 (30.759) -10.854 (34.553)
Median 145.548 -5.636
Min - Max 90.37 - 191.58 -65.71 - 49.04
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.622 (27.088) -5.551 (44.670)
Median 147.102 -11.512
Min - Max 108.82 - 200.23 -69.54 - 113.59
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.460 (21.352) -3.712 (37.984)
Median 156.505 -7.606
Min - Max 94.70 - 180.41 -74.91 - 72.74
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.714 (22.980) -8.458 (33.175)
Median 150.797 -14.432
Min - Max 106.91 - 188.09 -41.95 - 65.16
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.592 (33.170) -10.581 (44.799)
Median 148.501 -2.385
Min - Max 92.18 - 191.05 -78.77 - 64.35
\s\n
Parameter: Temperature
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 36.273 (1.136) NE (NE) 36.731 (1.142) NE (NE)
Median 36.131 NE 36.506 NE
Min - Max 34.07 - 38.59 NE - NE 34.97 - 39.04 NE - NE
BASELINE
n 15 15
Mean (SD) 36.763 (1.167) 36.707 (1.528)
Median 36.694 37.144
Min - Max 35.08 - 38.72 33.65 - 38.92
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 36.280 (0.543) -0.483 (1.022) 36.292 (1.378) -0.415 (1.957)
Median 36.194 -0.609 36.451 -0.344
Min - Max 35.37 - 37.06 -2.07 - 1.11 33.03 - 38.47 -4.72 - 2.24
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 37.090 (1.136) 0.328 (1.647) 36.577 (1.291) -0.130 (1.799)
Median 37.138 0.153 36.113 0.300
Min - Max 34.44 - 38.95 -2.34 - 2.85 34.86 - 39.29 -3.52 - 2.55
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 36.725 (1.003) -0.038 (1.441) 36.546 (1.008) -0.161 (1.701)
Median 36.616 0.029 36.378 -0.368
Min - Max 35.24 - 38.26 -3.25 - 2.34 35.08 - 38.17 -2.59 - 4.13
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 36.545 (1.070) -0.218 (1.859) 36.574 (1.024) -0.133 (1.994)
Median 36.299 -0.701 36.546 -0.436
Min - Max 34.87 - 39.00 -3.85 - 3.10 34.77 - 38.98 -2.74 - 4.07
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 37.038 (0.918) 0.275 (1.334) 36.823 (1.247) 0.117 (1.387)
Median 36.945 0.346 36.839 -0.476
Min - Max 35.71 - 38.45 -2.78 - 2.77 34.69 - 38.91 -1.76 - 3.06
\s\n
Parameter: Temperature
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 36.565 (1.112) NE (NE)
Median 36.681 NE
Min - Max 35.30 - 38.90 NE - NE
BASELINE
n 15
Mean (SD) 36.383 (0.963)
Median 36.496
Min - Max 34.71 - 37.92
WEEK 1 DAY 8
n 15 15
Mean (SD) 36.848 (0.936) 0.465 (1.458)
Median 36.973 0.399
Min - Max 35.28 - 38.18 -1.44 - 2.99
WEEK 2 DAY 15
n 15 15
Mean (SD) 36.620 (1.077) 0.237 (1.595)
Median 36.519 0.690
Min - Max 34.89 - 38.33 -3.02 - 2.47
WEEK 3 DAY 22
n 15 15
Mean (SD) 36.697 (0.694) 0.314 (1.312)
Median 36.679 0.841
Min - Max 35.14 - 37.64 -2.77 - 2.63
WEEK 4 DAY 29
n 15 15
Mean (SD) 36.738 (0.760) 0.355 (0.872)
Median 36.585 0.352
Min - Max 35.29 - 38.24 -0.91 - 2.14
WEEK 5 DAY 36
n 15 15
Mean (SD) 36.716 (1.056) 0.333 (1.344)
Median 36.404 0.500
Min - Max 35.26 - 38.64 -1.83 - 3.72
\s\n
Parameter: Weight
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 81.827 (23.644) NE (NE) 61.563 (19.272) NE (NE)
Median 80.182 NE 62.147 NE
Min - Max 40.48 - 133.35 NE - NE 23.27 - 92.39 NE - NE
BASELINE
n 15 15
Mean (SD) 76.532 (15.588) 70.870 (12.845)
Median 71.929 66.405
Min - Max 56.24 - 102.43 54.36 - 96.85
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 71.171 (19.805) -5.360 (23.082) 69.872 (17.781) -0.998 (20.176)
Median 65.106 -6.780 70.971 -2.628
Min - Max 47.03 - 123.95 -49.07 - 40.63 30.55 - 93.75 -35.86 - 28.87
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 80.484 (18.937) 3.952 (22.123) 72.940 (20.302) 2.070 (17.837)
Median 75.792 3.284 71.374 3.396
Min - Max 44.83 - 112.37 -36.68 - 35.07 35.00 - 106.69 -32.41 - 26.17
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 68.100 (15.095) -8.431 (18.100) 71.883 (18.376) 1.013 (22.760)
Median 66.175 -7.353 76.267 3.928
Min - Max 30.53 - 91.08 -46.15 - 29.48 20.87 - 95.04 -43.57 - 29.54
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 73.294 (18.861) -3.238 (18.094) 71.553 (17.090) 0.683 (16.404)
Median 76.829 -0.941 70.705 -1.527
Min - Max 24.32 - 98.14 -44.46 - 18.39 43.61 - 107.47 -26.14 - 43.89
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 66.719 (15.750) -9.812 (26.403) 68.162 (15.787) -2.708 (20.179)
Median 64.046 -5.370 67.480 -1.537
Min - Max 33.02 - 95.14 -69.42 - 26.72 45.71 - 102.63 -36.52 - 30.47
\s\n
Parameter: Weight
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 64.923 (16.678) NE (NE)
Median 62.745 NE
Min - Max 26.70 - 94.66 NE - NE
BASELINE
n 15
Mean (SD) 71.676 (16.922)
Median 68.883
Min - Max 27.15 - 107.89
WEEK 1 DAY 8
n 15 15
Mean (SD) 74.799 (13.706) 3.123 (21.964)
Median 71.374 4.336
Min - Max 53.19 - 96.54 -32.10 - 51.00
WEEK 2 DAY 15
n 15 15
Mean (SD) 67.267 (19.187) -4.409 (25.986)
Median 60.651 -5.246
Min - Max 35.56 - 102.05 -67.52 - 33.50
WEEK 3 DAY 22
n 15 15
Mean (SD) 70.442 (21.914) -1.234 (25.307)
Median 72.649 5.691
Min - Max 31.36 - 101.13 -45.69 - 32.28
WEEK 4 DAY 29
n 15 15
Mean (SD) 77.447 (21.174) 5.771 (25.479)
Median 86.161 19.614
Min - Max 41.60 - 112.40 -40.90 - 35.30
WEEK 5 DAY 36
n 15 15
Mean (SD) 65.688 (23.847) -5.988 (35.176)
Median 71.788 -7.456
Min - Max 12.04 - 114.55 -71.68 - 87.41
cfbt01 can handle n = 0 and outputs NE instead of infs and NAs
Code
cat(export_as_txt(res, lpp = 100))
Output
Parameter: Diastolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.385 (17.067) NE (NE) 106.381 (20.586) NE (NE)
Median 94.933 NE 111.133 NE
Min - Max 55.71 - 122.00 NE - NE 60.21 - 131.91 NE - NE
BASELINE
n 15 15
Mean (SD) 96.133 (22.458) 108.111 (15.074)
Median 93.328 108.951
Min - Max 60.58 - 136.59 83.44 - 131.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 98.977 (21.359) 2.844 (28.106) 104.110 (16.172) -4.001 (21.867)
Median 92.447 -4.066 107.703 3.227
Min - Max 67.55 - 130.37 -32.82 - 47.68 70.91 - 132.89 -52.94 - 28.63
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.758 (14.477) 3.626 (21.189) 97.473 (17.296) -10.638 (20.831)
Median 101.498 1.731 99.501 -9.727
Min - Max 71.98 - 122.81 -39.50 - 47.57 53.80 - 125.81 -55.15 - 25.26
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.101 (26.109) 2.968 (34.327) 91.984 (16.925) -16.127 (21.881)
Median 101.146 -0.271 91.244 -14.384
Min - Max 47.68 - 162.22 -47.87 - 76.64 67.80 - 119.72 -53.06 - 22.52
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.400 (22.273) 7.267 (30.740) 96.467 (19.451) -11.644 (25.922)
Median 98.168 2.510 97.385 -16.793
Min - Max 63.09 - 148.25 -38.43 - 61.90 63.35 - 131.57 -57.11 - 48.13
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.222 (18.536) -2.911 (28.873) 97.890 (20.701) -10.221 (27.593)
Median 90.799 -3.385 99.049 -11.319
Min - Max 63.55 - 139.11 -48.63 - 47.35 69.47 - 137.64 -54.38 - 37.85
\s\n
Parameter: Diastolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.468 (12.628) NE (NE)
Median 108.359 NE
Min - Max 83.29 - 127.17 NE - NE
BASELINE
n 15
Mean (SD) 103.149 (19.752)
Median 102.849
Min - Max 66.05 - 136.55
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.826 (19.027) -2.323 (25.018)
Median 103.058 -2.476
Min - Max 70.04 - 128.68 -55.15 - 41.81
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.272 (16.961) -8.877 (27.229)
Median 96.789 -10.155
Min - Max 63.45 - 117.47 -73.10 - 46.54
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.586 (13.560) -8.563 (21.713)
Median 98.398 -16.075
Min - Max 73.50 - 115.43 -37.90 - 32.66
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.338 (18.417) 5.189 (21.881)
Median 107.555 7.966
Min - Max 68.78 - 132.52 -33.96 - 41.50
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.317 (16.401) -7.832 (19.827)
Median 93.876 -4.665
Min - Max 71.91 - 138.54 -44.47 - 29.11
\s\n
Parameter: Systolic Blood Pressure
———————————————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
———————————————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.073 (33.511) NE (NE) 157.840 (34.393) NE (NE)
Median 156.169 NE 161.670 NE
Min - Max 78.31 - 210.70 NE - NE 79.76 - 210.40 NE - NE
BASELINE
n 15 15
Mean (SD) 145.925 (28.231) 152.007 (28.664)
Median 142.705 157.698
Min - Max 85.21 - 195.68 98.90 - 194.62
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.509 (21.097) 10.584 (34.598) 147.480 (33.473) -4.527 (48.895)
Median 160.711 5.802 155.030 2.758
Min - Max 126.84 - 185.53 -53.28 - 91.52 85.22 - 189.88 -77.34 - 90.98
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.202 (33.676) -1.723 (27.067) 136.892 (30.178) -15.115 (37.794)
Median 144.253 5.325 142.679 -14.083
Min - Max 62.56 - 203.66 -53.89 - 44.16 70.34 - 174.27 -83.07 - 62.39
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.887 (35.374) 8.962 (38.455) 149.761 (28.944) -2.247 (44.835)
Median 158.938 17.191 155.044 -1.796
Min - Max 112.32 - 218.83 -47.28 - 96.18 84.42 - 192.92 -110.20 - 94.02
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.159 (32.249) 4.234 (32.965) 156.043 (22.863) 4.036 (42.494)
Median 145.506 3.754 149.094 -10.000
Min - Max 69.37 - 210.43 -89.16 - 54.32 113.57 - 195.10 -71.44 - 77.75
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 155.964 (30.945) 10.039 (42.252) 156.387 (35.274) 4.380 (51.782)
Median 158.142 1.448 164.552 7.060
Min - Max 110.61 - 212.47 -53.91 - 90.45 63.28 - 198.79 -131.34 - 86.84
\s\n
Parameter: Systolic Blood Pressure
——————————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
——————————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.407 (22.311) NE (NE)
Median 149.556 NE
Min - Max 108.21 - 184.88 NE - NE
BASELINE
n 15
Mean (SD) 154.173 (26.317)
Median 155.282
Min - Max 86.65 - 192.68
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.319 (30.759) -10.854 (34.553)
Median 145.548 -5.636
Min - Max 90.37 - 191.58 -65.71 - 49.04
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.622 (27.088) -5.551 (44.670)
Median 147.102 -11.512
Min - Max 108.82 - 200.23 -69.54 - 113.59
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.460 (21.352) -3.712 (37.984)
Median 156.505 -7.606
Min - Max 94.70 - 180.41 -74.91 - 72.74
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.714 (22.980) -8.458 (33.175)
Median 150.797 -14.432
Min - Max 106.91 - 188.09 -41.95 - 65.16
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.592 (33.170) -10.581 (44.799)
Median 148.501 -2.385
Min - Max 92.18 - 191.05 -78.77 - 64.35
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