Nothing
tests/testthat/_snaps/vst01.md
In chevron: Standard TLGs for Clinical Trials Reporting
vst01 functions with default argument value return expected result with test data
Code
cat(export_as_txt(res, lpp = 200))
Output
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.4 (17.1) NE (NE) 106.4 (20.6) NE (NE)
Median 94.9 NE 111.1 NE
Min - Max 56 - 122 NE - NE 60 - 132 NE - NE
BASELINE
n 15 15
Mean (SD) 96.1 (22.5) 108.1 (15.1)
Median 93.3 109.0
Min - Max 61 - 137 83 - 132
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 99.0 (21.4) 2.8 (28.1) 104.1 (16.2) -4.0 (21.9)
Median 92.4 -4.1 107.7 3.2
Min - Max 68 - 130 -33 - 48 71 - 133 -53 - 29
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.8 (14.5) 3.6 (21.2) 97.5 (17.3) -10.6 (20.8)
Median 101.5 1.7 99.5 -9.7
Min - Max 72 - 123 -40 - 48 54 - 126 -55 - 25
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.1 (26.1) 3.0 (34.3) 92.0 (16.9) -16.1 (21.9)
Median 101.1 -0.3 91.2 -14.4
Min - Max 48 - 162 -48 - 77 68 - 120 -53 - 23
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.4 (22.3) 7.3 (30.7) 96.5 (19.5) -11.6 (25.9)
Median 98.2 2.5 97.4 -16.8
Min - Max 63 - 148 -38 - 62 63 - 132 -57 - 48
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.2 (18.5) -2.9 (28.9) 97.9 (20.7) -10.2 (27.6)
Median 90.8 -3.4 99.0 -11.3
Min - Max 64 - 139 -49 - 47 69 - 138 -54 - 38
\s\n
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.5 (12.6) NE (NE)
Median 108.4 NE
Min - Max 83 - 127 NE - NE
BASELINE
n 15
Mean (SD) 103.1 (19.8)
Median 102.8
Min - Max 66 - 137
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.8 (19.0) -2.3 (25.0)
Median 103.1 -2.5
Min - Max 70 - 129 -55 - 42
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.3 (17.0) -8.9 (27.2)
Median 96.8 -10.2
Min - Max 63 - 117 -73 - 47
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.6 (13.6) -8.6 (21.7)
Median 98.4 -16.1
Min - Max 74 - 115 -38 - 33
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.3 (18.4) 5.2 (21.9)
Median 107.6 8.0
Min - Max 69 - 133 -34 - 42
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.3 (16.4) -7.8 (19.8)
Median 93.9 -4.7
Min - Max 72 - 139 -44 - 29
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.1 (33.5) NE (NE) 157.8 (34.4) NE (NE)
Median 156.2 NE 161.7 NE
Min - Max 78 - 211 NE - NE 80 - 210 NE - NE
BASELINE
n 15 15
Mean (SD) 145.9 (28.2) 152.0 (28.7)
Median 142.7 157.7
Min - Max 85 - 196 99 - 195
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.5 (21.1) 10.6 (34.6) 147.5 (33.5) -4.5 (48.9)
Median 160.7 5.8 155.0 2.8
Min - Max 127 - 186 -53 - 92 85 - 190 -77 - 91
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.2 (33.7) -1.7 (27.1) 136.9 (30.2) -15.1 (37.8)
Median 144.3 5.3 142.7 -14.1
Min - Max 63 - 204 -54 - 44 70 - 174 -83 - 62
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.9 (35.4) 9.0 (38.5) 149.8 (28.9) -2.2 (44.8)
Median 158.9 17.2 155.0 -1.8
Min - Max 112 - 219 -47 - 96 84 - 193 -110 - 94
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.2 (32.2) 4.2 (33.0) 156.0 (22.9) 4.0 (42.5)
Median 145.5 3.8 149.1 -10.0
Min - Max 69 - 210 -89 - 54 114 - 195 -71 - 78
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 156.0 (30.9) 10.0 (42.3) 156.4 (35.3) 4.4 (51.8)
Median 158.1 1.4 164.6 7.1
Min - Max 111 - 212 -54 - 90 63 - 199 -131 - 87
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.4 (22.3) NE (NE)
Median 149.6 NE
Min - Max 108 - 185 NE - NE
BASELINE
n 15
Mean (SD) 154.2 (26.3)
Median 155.3
Min - Max 87 - 193
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.3 (30.8) -10.9 (34.6)
Median 145.5 -5.6
Min - Max 90 - 192 -66 - 49
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.6 (27.1) -5.6 (44.7)
Median 147.1 -11.5
Min - Max 109 - 200 -70 - 114
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.5 (21.4) -3.7 (38.0)
Median 156.5 -7.6
Min - Max 95 - 180 -75 - 73
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.7 (23.0) -8.5 (33.2)
Median 150.8 -14.4
Min - Max 107 - 188 -42 - 65
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.6 (33.2) -10.6 (44.8)
Median 148.5 -2.4
Min - Max 92 - 191 -79 - 64
run vst01 works as expected
Code
cat(export_as_txt(res, lpp = 200))
Output
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.4 (17.1) NE (NE) 106.4 (20.6) NE (NE)
Median 94.9 NE 111.1 NE
Min - Max 56 - 122 NE - NE 60 - 132 NE - NE
BASELINE
n 15 15
Mean (SD) 96.1 (22.5) 108.1 (15.1)
Median 93.3 109.0
Min - Max 61 - 137 83 - 132
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 99.0 (21.4) 2.8 (28.1) 104.1 (16.2) -4.0 (21.9)
Median 92.4 -4.1 107.7 3.2
Min - Max 68 - 130 -33 - 48 71 - 133 -53 - 29
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.8 (14.5) 3.6 (21.2) 97.5 (17.3) -10.6 (20.8)
Median 101.5 1.7 99.5 -9.7
Min - Max 72 - 123 -40 - 48 54 - 126 -55 - 25
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.1 (26.1) 3.0 (34.3) 92.0 (16.9) -16.1 (21.9)
Median 101.1 -0.3 91.2 -14.4
Min - Max 48 - 162 -48 - 77 68 - 120 -53 - 23
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.4 (22.3) 7.3 (30.7) 96.5 (19.5) -11.6 (25.9)
Median 98.2 2.5 97.4 -16.8
Min - Max 63 - 148 -38 - 62 63 - 132 -57 - 48
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.2 (18.5) -2.9 (28.9) 97.9 (20.7) -10.2 (27.6)
Median 90.8 -3.4 99.0 -11.3
Min - Max 64 - 139 -49 - 47 69 - 138 -54 - 38
\s\n
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.5 (12.6) NE (NE)
Median 108.4 NE
Min - Max 83 - 127 NE - NE
BASELINE
n 15
Mean (SD) 103.1 (19.8)
Median 102.8
Min - Max 66 - 137
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.8 (19.0) -2.3 (25.0)
Median 103.1 -2.5
Min - Max 70 - 129 -55 - 42
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.3 (17.0) -8.9 (27.2)
Median 96.8 -10.2
Min - Max 63 - 117 -73 - 47
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.6 (13.6) -8.6 (21.7)
Median 98.4 -16.1
Min - Max 74 - 115 -38 - 33
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.3 (18.4) 5.2 (21.9)
Median 107.6 8.0
Min - Max 69 - 133 -34 - 42
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.3 (16.4) -7.8 (19.8)
Median 93.9 -4.7
Min - Max 72 - 139 -44 - 29
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.1 (33.5) NE (NE) 157.8 (34.4) NE (NE)
Median 156.2 NE 161.7 NE
Min - Max 78 - 211 NE - NE 80 - 210 NE - NE
BASELINE
n 15 15
Mean (SD) 145.9 (28.2) 152.0 (28.7)
Median 142.7 157.7
Min - Max 85 - 196 99 - 195
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.5 (21.1) 10.6 (34.6) 147.5 (33.5) -4.5 (48.9)
Median 160.7 5.8 155.0 2.8
Min - Max 127 - 186 -53 - 92 85 - 190 -77 - 91
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.2 (33.7) -1.7 (27.1) 136.9 (30.2) -15.1 (37.8)
Median 144.3 5.3 142.7 -14.1
Min - Max 63 - 204 -54 - 44 70 - 174 -83 - 62
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.9 (35.4) 9.0 (38.5) 149.8 (28.9) -2.2 (44.8)
Median 158.9 17.2 155.0 -1.8
Min - Max 112 - 219 -47 - 96 84 - 193 -110 - 94
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.2 (32.2) 4.2 (33.0) 156.0 (22.9) 4.0 (42.5)
Median 145.5 3.8 149.1 -10.0
Min - Max 69 - 210 -89 - 54 114 - 195 -71 - 78
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 156.0 (30.9) 10.0 (42.3) 156.4 (35.3) 4.4 (51.8)
Median 158.1 1.4 164.6 7.1
Min - Max 111 - 212 -54 - 90 63 - 199 -131 - 87
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.4 (22.3) NE (NE)
Median 149.6 NE
Min - Max 108 - 185 NE - NE
BASELINE
n 15
Mean (SD) 154.2 (26.3)
Median 155.3
Min - Max 87 - 193
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.3 (30.8) -10.9 (34.6)
Median 145.5 -5.6
Min - Max 90 - 192 -66 - 49
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.6 (27.1) -5.6 (44.7)
Median 147.1 -11.5
Min - Max 109 - 200 -70 - 114
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.5 (21.4) -3.7 (38.0)
Median 156.5 -7.6
Min - Max 95 - 180 -75 - 73
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.7 (23.0) -8.5 (33.2)
Median 150.8 -14.4
Min - Max 107 - 188 -42 - 65
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.6 (33.2) -10.6 (44.8)
Median 148.5 -2.4
Min - Max 92 - 191 -79 - 64
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vst01 functions with default argument value return expected result with test data
Code
cat(export_as_txt(res, lpp = 200))
Output
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.4 (17.1) NE (NE) 106.4 (20.6) NE (NE)
Median 94.9 NE 111.1 NE
Min - Max 56 - 122 NE - NE 60 - 132 NE - NE
BASELINE
n 15 15
Mean (SD) 96.1 (22.5) 108.1 (15.1)
Median 93.3 109.0
Min - Max 61 - 137 83 - 132
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 99.0 (21.4) 2.8 (28.1) 104.1 (16.2) -4.0 (21.9)
Median 92.4 -4.1 107.7 3.2
Min - Max 68 - 130 -33 - 48 71 - 133 -53 - 29
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.8 (14.5) 3.6 (21.2) 97.5 (17.3) -10.6 (20.8)
Median 101.5 1.7 99.5 -9.7
Min - Max 72 - 123 -40 - 48 54 - 126 -55 - 25
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.1 (26.1) 3.0 (34.3) 92.0 (16.9) -16.1 (21.9)
Median 101.1 -0.3 91.2 -14.4
Min - Max 48 - 162 -48 - 77 68 - 120 -53 - 23
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.4 (22.3) 7.3 (30.7) 96.5 (19.5) -11.6 (25.9)
Median 98.2 2.5 97.4 -16.8
Min - Max 63 - 148 -38 - 62 63 - 132 -57 - 48
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.2 (18.5) -2.9 (28.9) 97.9 (20.7) -10.2 (27.6)
Median 90.8 -3.4 99.0 -11.3
Min - Max 64 - 139 -49 - 47 69 - 138 -54 - 38
\s\n
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.5 (12.6) NE (NE)
Median 108.4 NE
Min - Max 83 - 127 NE - NE
BASELINE
n 15
Mean (SD) 103.1 (19.8)
Median 102.8
Min - Max 66 - 137
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.8 (19.0) -2.3 (25.0)
Median 103.1 -2.5
Min - Max 70 - 129 -55 - 42
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.3 (17.0) -8.9 (27.2)
Median 96.8 -10.2
Min - Max 63 - 117 -73 - 47
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.6 (13.6) -8.6 (21.7)
Median 98.4 -16.1
Min - Max 74 - 115 -38 - 33
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.3 (18.4) 5.2 (21.9)
Median 107.6 8.0
Min - Max 69 - 133 -34 - 42
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.3 (16.4) -7.8 (19.8)
Median 93.9 -4.7
Min - Max 72 - 139 -44 - 29
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.1 (33.5) NE (NE) 157.8 (34.4) NE (NE)
Median 156.2 NE 161.7 NE
Min - Max 78 - 211 NE - NE 80 - 210 NE - NE
BASELINE
n 15 15
Mean (SD) 145.9 (28.2) 152.0 (28.7)
Median 142.7 157.7
Min - Max 85 - 196 99 - 195
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.5 (21.1) 10.6 (34.6) 147.5 (33.5) -4.5 (48.9)
Median 160.7 5.8 155.0 2.8
Min - Max 127 - 186 -53 - 92 85 - 190 -77 - 91
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.2 (33.7) -1.7 (27.1) 136.9 (30.2) -15.1 (37.8)
Median 144.3 5.3 142.7 -14.1
Min - Max 63 - 204 -54 - 44 70 - 174 -83 - 62
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.9 (35.4) 9.0 (38.5) 149.8 (28.9) -2.2 (44.8)
Median 158.9 17.2 155.0 -1.8
Min - Max 112 - 219 -47 - 96 84 - 193 -110 - 94
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.2 (32.2) 4.2 (33.0) 156.0 (22.9) 4.0 (42.5)
Median 145.5 3.8 149.1 -10.0
Min - Max 69 - 210 -89 - 54 114 - 195 -71 - 78
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 156.0 (30.9) 10.0 (42.3) 156.4 (35.3) 4.4 (51.8)
Median 158.1 1.4 164.6 7.1
Min - Max 111 - 212 -54 - 90 63 - 199 -131 - 87
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.4 (22.3) NE (NE)
Median 149.6 NE
Min - Max 108 - 185 NE - NE
BASELINE
n 15
Mean (SD) 154.2 (26.3)
Median 155.3
Min - Max 87 - 193
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.3 (30.8) -10.9 (34.6)
Median 145.5 -5.6
Min - Max 90 - 192 -66 - 49
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.6 (27.1) -5.6 (44.7)
Median 147.1 -11.5
Min - Max 109 - 200 -70 - 114
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.5 (21.4) -3.7 (38.0)
Median 156.5 -7.6
Min - Max 95 - 180 -75 - 73
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.7 (23.0) -8.5 (33.2)
Median 150.8 -14.4
Min - Max 107 - 188 -42 - 65
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.6 (33.2) -10.6 (44.8)
Median 148.5 -2.4
Min - Max 92 - 191 -79 - 64
run vst01 works as expected
Code
cat(export_as_txt(res, lpp = 200))
Output
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 94.4 (17.1) NE (NE) 106.4 (20.6) NE (NE)
Median 94.9 NE 111.1 NE
Min - Max 56 - 122 NE - NE 60 - 132 NE - NE
BASELINE
n 15 15
Mean (SD) 96.1 (22.5) 108.1 (15.1)
Median 93.3 109.0
Min - Max 61 - 137 83 - 132
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 99.0 (21.4) 2.8 (28.1) 104.1 (16.2) -4.0 (21.9)
Median 92.4 -4.1 107.7 3.2
Min - Max 68 - 130 -33 - 48 71 - 133 -53 - 29
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 99.8 (14.5) 3.6 (21.2) 97.5 (17.3) -10.6 (20.8)
Median 101.5 1.7 99.5 -9.7
Min - Max 72 - 123 -40 - 48 54 - 126 -55 - 25
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 99.1 (26.1) 3.0 (34.3) 92.0 (16.9) -16.1 (21.9)
Median 101.1 -0.3 91.2 -14.4
Min - Max 48 - 162 -48 - 77 68 - 120 -53 - 23
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 103.4 (22.3) 7.3 (30.7) 96.5 (19.5) -11.6 (25.9)
Median 98.2 2.5 97.4 -16.8
Min - Max 63 - 148 -38 - 62 63 - 132 -57 - 48
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 93.2 (18.5) -2.9 (28.9) 97.9 (20.7) -10.2 (27.6)
Median 90.8 -3.4 99.0 -11.3
Min - Max 64 - 139 -49 - 47 69 - 138 -54 - 38
\s\n
Parameter: Diastolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 106.5 (12.6) NE (NE)
Median 108.4 NE
Min - Max 83 - 127 NE - NE
BASELINE
n 15
Mean (SD) 103.1 (19.8)
Median 102.8
Min - Max 66 - 137
WEEK 1 DAY 8
n 15 15
Mean (SD) 100.8 (19.0) -2.3 (25.0)
Median 103.1 -2.5
Min - Max 70 - 129 -55 - 42
WEEK 2 DAY 15
n 15 15
Mean (SD) 94.3 (17.0) -8.9 (27.2)
Median 96.8 -10.2
Min - Max 63 - 117 -73 - 47
WEEK 3 DAY 22
n 15 15
Mean (SD) 94.6 (13.6) -8.6 (21.7)
Median 98.4 -16.1
Min - Max 74 - 115 -38 - 33
WEEK 4 DAY 29
n 15 15
Mean (SD) 108.3 (18.4) 5.2 (21.9)
Median 107.6 8.0
Min - Max 69 - 133 -34 - 42
WEEK 5 DAY 36
n 15 15
Mean (SD) 95.3 (16.4) -7.8 (19.8)
Median 93.9 -4.7
Min - Max 72 - 139 -44 - 29
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————————————————————————————————————
A: Drug X B: Placebo
Change from Change from
Value at Visit Baseline Value at Visit Baseline
Analysis Visit (N=15) (N=15) (N=15) (N=15)
————————————————————————————————————————————————————————————————————————————————————————
SCREENING
n 15 0 15 0
Mean (SD) 154.1 (33.5) NE (NE) 157.8 (34.4) NE (NE)
Median 156.2 NE 161.7 NE
Min - Max 78 - 211 NE - NE 80 - 210 NE - NE
BASELINE
n 15 15
Mean (SD) 145.9 (28.2) 152.0 (28.7)
Median 142.7 157.7
Min - Max 85 - 196 99 - 195
WEEK 1 DAY 8
n 15 15 15 15
Mean (SD) 156.5 (21.1) 10.6 (34.6) 147.5 (33.5) -4.5 (48.9)
Median 160.7 5.8 155.0 2.8
Min - Max 127 - 186 -53 - 92 85 - 190 -77 - 91
WEEK 2 DAY 15
n 15 15 15 15
Mean (SD) 144.2 (33.7) -1.7 (27.1) 136.9 (30.2) -15.1 (37.8)
Median 144.3 5.3 142.7 -14.1
Min - Max 63 - 204 -54 - 44 70 - 174 -83 - 62
WEEK 3 DAY 22
n 15 15 15 15
Mean (SD) 154.9 (35.4) 9.0 (38.5) 149.8 (28.9) -2.2 (44.8)
Median 158.9 17.2 155.0 -1.8
Min - Max 112 - 219 -47 - 96 84 - 193 -110 - 94
WEEK 4 DAY 29
n 15 15 15 15
Mean (SD) 150.2 (32.2) 4.2 (33.0) 156.0 (22.9) 4.0 (42.5)
Median 145.5 3.8 149.1 -10.0
Min - Max 69 - 210 -89 - 54 114 - 195 -71 - 78
WEEK 5 DAY 36
n 15 15 15 15
Mean (SD) 156.0 (30.9) 10.0 (42.3) 156.4 (35.3) 4.4 (51.8)
Median 158.1 1.4 164.6 7.1
Min - Max 111 - 212 -54 - 90 63 - 199 -131 - 87
\s\n
Parameter: Systolic Blood Pressure
————————————————————————————————————————————————————————
C: Combination
Change from
Value at Visit Baseline
Analysis Visit (N=15) (N=15)
————————————————————————————————————————————————————————
SCREENING
n 15 0
Mean (SD) 152.4 (22.3) NE (NE)
Median 149.6 NE
Min - Max 108 - 185 NE - NE
BASELINE
n 15
Mean (SD) 154.2 (26.3)
Median 155.3
Min - Max 87 - 193
WEEK 1 DAY 8
n 15 15
Mean (SD) 143.3 (30.8) -10.9 (34.6)
Median 145.5 -5.6
Min - Max 90 - 192 -66 - 49
WEEK 2 DAY 15
n 15 15
Mean (SD) 148.6 (27.1) -5.6 (44.7)
Median 147.1 -11.5
Min - Max 109 - 200 -70 - 114
WEEK 3 DAY 22
n 15 15
Mean (SD) 150.5 (21.4) -3.7 (38.0)
Median 156.5 -7.6
Min - Max 95 - 180 -75 - 73
WEEK 4 DAY 29
n 15 15
Mean (SD) 145.7 (23.0) -8.5 (33.2)
Median 150.8 -14.4
Min - Max 107 - 188 -42 - 65
WEEK 5 DAY 36
n 15 15
Mean (SD) 143.6 (33.2) -10.6 (44.8)
Median 148.5 -2.4
Min - Max 92 - 191 -79 - 64
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