targetDel | R Documentation |
Find the difference between the average subpopulation treatment effect and the desired one
targetDel(z2, kkk, muminusmu0, kappa, rhovec, sigma, cDel)
z2 |
the standardized biomarker value of the second biomarker |
kkk |
the researchers' weighting preference between the two biomarkers |
muminusmu0 |
a number of the difference between the mean of outcome and the minimal clinically important treatment effect |
kappa |
a number of the correlation coefficient between two biomarkers |
rhovec |
a numeric vector of two correlation coefficients between the output and two biomarkers |
sigma |
a number of the standard deviation of outcome |
cDel |
the desired average subpopulation treatment effect |
the difference between the average subpopulation treatment effect and the desired one
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