tbl_hierarchical_rate_and_count.md
In crane: Supplements the 'gtsummary' Package for Pharmaceutical Reporting

tbl_hierarchical_rate_and_count() works

Code
  as.data.frame(tbl)
Output
        Body System or Organ Class  \n    Dictionary-Derived Term Placebo  \n(N = 86) Xanomeline High Dose  \n(N = 84) Xanomeline Low Dose  \n(N = 84) All Participants  \n(N = 254)
  1  Total number of participants with at least one adverse event            3 (3.5%)                         2 (2.4%)                        1 (1.2%)                      6 (2.4%)
  2                                Overall total number of events                   5                                4                               1                            10
  3                                    GASTROINTESTINAL DISORDERS                <NA>                             <NA>                            <NA>                          <NA>
  4  Total number of participants with at least one adverse event            3 (3.5%)                                0                               0                      3 (1.2%)
  5                                        Total number of events                   3                                0                               0                             3
  6                                                     DIARRHOEA            3 (3.5%)                                0                               0                      3 (1.2%)
  7          GENERAL DISORDERS AND ADMINISTRATION SITE CONDITIONS                <NA>                             <NA>                            <NA>                          <NA>
  8  Total number of participants with at least one adverse event            1 (1.2%)                         2 (2.4%)                        1 (1.2%)                      4 (1.6%)
  9                                        Total number of events                   2                                4                               1                             7
  10                                    APPLICATION SITE ERYTHEMA            1 (1.2%)                         1 (1.2%)                        1 (1.2%)                      3 (1.2%)
  11                                    APPLICATION SITE PRURITUS            1 (1.2%)                         2 (2.4%)                               0                      3 (1.2%)
  12                                                      FATIGUE                   0                         1 (1.2%)                               0                      1 (0.4%)

Code
  as.data.frame(tbl)
Output
     Body System or Organ Class  \n    High Level Term  \n        Dictionary-Derived Term Placebo  \n(N = 86) Xanomeline High Dose  \n(N = 84) Xanomeline Low Dose  \n(N = 84) All Participants  \n(N = 254)
  1                          Total number of participants with at least one adverse event            3 (3.5%)                         2 (2.4%)                        1 (1.2%)                      6 (2.4%)
  2                                                        Overall total number of events                   5                                4                               1                            10
  3                                                            GASTROINTESTINAL DISORDERS                <NA>                             <NA>                            <NA>                          <NA>
  4                          Total number of participants with at least one adverse event            3 (3.5%)                                0                               0                      3 (1.2%)
  5                                                                Total number of events                   3                                0                               0                             3
  6                                                                              HLT_0148                <NA>                             <NA>                            <NA>                          <NA>
  7                          Total number of participants with at least one adverse event            3 (3.5%)                                0                               0                      3 (1.2%)
  8                                                                Total number of events                   3                                0                               0                             3
  9                                                                             DIARRHOEA            3 (3.5%)                                0                               0                      3 (1.2%)
  10                                 GENERAL DISORDERS AND ADMINISTRATION SITE CONDITIONS                <NA>                             <NA>                            <NA>                          <NA>
  11                         Total number of participants with at least one adverse event            1 (1.2%)                         2 (2.4%)                        1 (1.2%)                      4 (1.6%)
  12                                                               Total number of events                   2                                4                               1                             7
  13                                                                             HLT_0043                <NA>                             <NA>                            <NA>                          <NA>
  14                         Total number of participants with at least one adverse event                   0                         1 (1.2%)                               0                      1 (0.4%)
  15                                                               Total number of events                   0                                1                               0                             1
  16                                                                              FATIGUE                   0                         1 (1.2%)                               0                      1 (0.4%)
  17                                                                             HLT_0317                <NA>                             <NA>                            <NA>                          <NA>
  18                         Total number of participants with at least one adverse event            1 (1.2%)                         2 (2.4%)                               0                      3 (1.2%)
  19                                                               Total number of events                   1                                2                               0                             3
  20                                                            APPLICATION SITE PRURITUS            1 (1.2%)                         2 (2.4%)                               0                      3 (1.2%)
  21                                                                             HLT_0617                <NA>                             <NA>                            <NA>                          <NA>
  22                         Total number of participants with at least one adverse event            1 (1.2%)                         1 (1.2%)                        1 (1.2%)                      3 (1.2%)
  23                                                               Total number of events                   1                                1                               1                             3
  24                                                            APPLICATION SITE ERYTHEMA            1 (1.2%)                         1 (1.2%)                        1 (1.2%)                      3 (1.2%)

tbl_hierarchical_rate_and_count() works only with 2 or 3 variables

Code
  tbl <- tbl_hierarchical_rate_and_count(ADAE_subset, denominator = cards::ADSL,
  by = TRTA, variables = c(AEBODSYS), sort = "descending")
Condition
  Error in `tbl_hierarchical_rate_and_count()`:
  ! The `variables` argument must select 2 or 3 columns
  i For a single variable summary, use `gtsummary::hierarchical(variables="AEBODSYS")`

Code
  tbl <- tbl_hierarchical_rate_and_count(ADAE_subset, denominator = cards::ADSL,
  by = TRTA, variables = c(SEX, AEBODSYS, AEDECOD, SAFFL), sort = "descending")
Condition
  Error in `tbl_hierarchical_rate_and_count()`:
  ! The `variables` argument must select 2 or 3 columns
  i Columns select are typically `c(AEBODSYS, AEDECOD)` or `c(AEBODSYS, AEHLT, AEDECOD)`