doseRecords: Random Effect Analysis

In dfmeta: Meta-Analysis of Phase I Dose-Finding Early Clinical Trials

Description

This function make a random effects analysis that can be used after in the random effects model based algorithm.

Usage

doseRecords(data)

Arguments

data	a data frame containing information for each patient at each simulation and trial.

Author(s)

Artemis Toumazi <[e-mail]>, Sarah Zohar <[e-mail]>, Anand N. Vidyashankar <[e-mail]>, Jie Xu <[e-mail]> and Moreno Ursino <[e-mail]>

References

Zohar, S. , Katsahian, S. and O'Quigley, J. (2011), An approach to meta analysis of dose finding studies. Statist. Med., <doi:10.1002/sim.4121>.

See Also

MA_estimates, glimem

Examples

  ################################################################
  ### Give a toxicity data for each simulation and each trial. ###
  ################################################################
  
  ### Using a toxicity data for each simulation and each trial including in the dfmeta package.
  data("Toxdata") 
  dim(Toxdata)
  colnames(Toxdata)
  
  ## NOTE: The toxicity dataset must have the same structure as below. ##
  ## Check it before running the VarWT function! ##
  str(Toxdata)
  
  analyf0 <- Toxdata[order(Toxdata$simulation), ]


  ####################################################
  ## Taking the records from random effect analysis ##
  ####################################################
  rec <- doseRecords(analyf0)

dfmeta documentation built on May 1, 2019, 7:59 p.m.