drsmooth: Dose-Response Modeling with Smoothing Splines

Provides tools for assessing the shape of a dose-response curve by testing linearity and non-linearity at user-defined cut-offs. It also provides two methods of estimating a threshold dose, or the dose at which the dose-response function transitions to significantly increasing: bi-linear (based on pkg 'segmented') and smoothed with splines (based on pkg 'mgcv').

AuthorGreg Hixon [aut], Chad Thompson [aut], Anne Bichteler [aut, cre], Liz Abraham [ctb]
Date of publication2015-09-25 00:01:50
MaintainerAnne Bichteler <abichteler@toxstrategies.com>
LicenseGPL (>= 3)
Version1.9.0

View on CRAN

Files in this package

drsmooth
drsmooth/inst
drsmooth/inst/CITATION
drsmooth/inst/tests
drsmooth/inst/tests/test-prelimstats.r
drsmooth/inst/tests/test-noel.r
drsmooth/inst/tests/test-spline.r
drsmooth/inst/tests/test-nlaad.r
drsmooth/tests
drsmooth/tests/test-all.R
drsmooth/NAMESPACE
drsmooth/NEWS
drsmooth/data
drsmooth/data/DRdata.rda
drsmooth/data/DIdata.rda
drsmooth/R
drsmooth/R/lbcd.r
drsmooth/R/dichot_smooth.R
drsmooth/R/prelimstats.r
drsmooth/R/drsmooth.print.r
drsmooth/R/fishers.exact.R drsmooth/R/dunns.R
drsmooth/R/segment.plot.r
drsmooth/R/noel.r
drsmooth/R/DRdata.R drsmooth/R/drsmooth.R
drsmooth/R/pkg_prep.r
drsmooth/R/bartlett.r
drsmooth/R/chisquare.r
drsmooth/R/jonckheere.r
drsmooth/R/drsmooth-package.R
drsmooth/R/segment.print.r
drsmooth/R/smooth.R
drsmooth/R/nlbcd.r
drsmooth/R/segment.r
drsmooth/R/nlaad.r
drsmooth/R/dunnetts.format.r
drsmooth/R/dunnettst3.r
drsmooth/R/DIdata.R drsmooth/R/firstDeriv.R
drsmooth/R/dosefactor.r
drsmooth/R/outlier.r
drsmooth/R/dunnetts.R
drsmooth/R/dunns.format.r
drsmooth/R/expand.R
drsmooth/R/spline.plot.r
drsmooth/R/shapiro.r
drsmooth/MD5
drsmooth/DESCRIPTION
drsmooth/man
drsmooth/man/segment.print.Rd drsmooth/man/segment.Rd drsmooth/man/jonckheere.Rd drsmooth/man/dunnetts.Rd drsmooth/man/segment.plot.Rd drsmooth/man/drsmooth.print.Rd drsmooth/man/dunns.Rd drsmooth/man/drsmooth-package.Rd drsmooth/man/nlaad.Rd drsmooth/man/spline.plot.Rd drsmooth/man/firstDeriv.Rd drsmooth/man/dunnettst3.Rd drsmooth/man/pkg_prep.Rd drsmooth/man/DRdata.Rd drsmooth/man/fishers.exact.Rd drsmooth/man/dosefactor.Rd drsmooth/man/nlbcd.Rd drsmooth/man/bartlett.Rd drsmooth/man/DIdata.Rd drsmooth/man/noel.Rd drsmooth/man/lbcd.Rd drsmooth/man/dunns.format.Rd drsmooth/man/outlier.Rd drsmooth/man/chisquare.Rd drsmooth/man/dichot_smooth.Rd drsmooth/man/shapiro.Rd drsmooth/man/expand.Rd drsmooth/man/dunnetts.format.Rd drsmooth/man/drsmooth.Rd drsmooth/man/prelimstats.Rd drsmooth/man/smooth.Rd

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