drsmooth: Dose-Response Modeling with Smoothing Splines

Provides tools for assessing the shape of a dose-response curve by testing linearity and non-linearity at user-defined cut-offs. It also provides two methods of estimating a threshold dose, or the dose at which the dose-response function transitions to significantly increasing: bi-linear (based on pkg 'segmented') and smoothed with splines (based on pkg 'mgcv').

AuthorGreg Hixon [aut], Chad Thompson [aut], Anne Bichteler [aut, cre], Liz Abraham [ctb]
Date of publication2015-09-25 00:01:50
MaintainerAnne Bichteler <abichteler@toxstrategies.com>
LicenseGPL (>= 3)
Version1.9.0

View on CRAN

Functions

bartlett Man page
chisquare Man page
dichot_smooth Man page
DIdata Man page
dosefactor Man page
DRdata Man page
drsmooth Man page
drsmooth-package Man page
drsmooth.print Man page
dunnetts Man page
dunnetts.format Man page
dunnettst3 Man page
dunns Man page
dunns.format Man page
expand Man page
firstDeriv Man page
fishers.exact Man page
jonckheere Man page
lbcd Man page
new.prelimstats Man page
nlaad Man page
nlbcd Man page
noel Man page
outlier Man page
pkg_prep Man page
prelimstats Man page
segment Man page
segment.plot Man page
segment.print Man page
shapiro Man page
smooth Man page
spline.plot Man page
validate.prelimstats Man page

Files

drsmooth
drsmooth/inst
drsmooth/inst/CITATION
drsmooth/inst/tests
drsmooth/inst/tests/test-prelimstats.r
drsmooth/inst/tests/test-noel.r
drsmooth/inst/tests/test-spline.r
drsmooth/inst/tests/test-nlaad.r
drsmooth/tests
drsmooth/tests/test-all.R
drsmooth/NAMESPACE
drsmooth/NEWS
drsmooth/data
drsmooth/data/DRdata.rda
drsmooth/data/DIdata.rda
drsmooth/R
drsmooth/R/lbcd.r
drsmooth/R/dichot_smooth.R
drsmooth/R/prelimstats.r
drsmooth/R/drsmooth.print.r
drsmooth/R/fishers.exact.R drsmooth/R/dunns.R
drsmooth/R/segment.plot.r
drsmooth/R/noel.r
drsmooth/R/DRdata.R drsmooth/R/drsmooth.R
drsmooth/R/pkg_prep.r
drsmooth/R/bartlett.r
drsmooth/R/chisquare.r
drsmooth/R/jonckheere.r
drsmooth/R/drsmooth-package.R
drsmooth/R/segment.print.r
drsmooth/R/smooth.R
drsmooth/R/nlbcd.r
drsmooth/R/segment.r
drsmooth/R/nlaad.r
drsmooth/R/dunnetts.format.r
drsmooth/R/dunnettst3.r
drsmooth/R/DIdata.R drsmooth/R/firstDeriv.R
drsmooth/R/dosefactor.r
drsmooth/R/outlier.r
drsmooth/R/dunnetts.R
drsmooth/R/dunns.format.r
drsmooth/R/expand.R
drsmooth/R/spline.plot.r
drsmooth/R/shapiro.r
drsmooth/MD5
drsmooth/DESCRIPTION
drsmooth/man
drsmooth/man/segment.print.Rd drsmooth/man/segment.Rd drsmooth/man/jonckheere.Rd drsmooth/man/dunnetts.Rd drsmooth/man/segment.plot.Rd drsmooth/man/drsmooth.print.Rd drsmooth/man/dunns.Rd drsmooth/man/drsmooth-package.Rd drsmooth/man/nlaad.Rd drsmooth/man/spline.plot.Rd drsmooth/man/firstDeriv.Rd drsmooth/man/dunnettst3.Rd drsmooth/man/pkg_prep.Rd drsmooth/man/DRdata.Rd drsmooth/man/fishers.exact.Rd drsmooth/man/dosefactor.Rd drsmooth/man/nlbcd.Rd drsmooth/man/bartlett.Rd drsmooth/man/DIdata.Rd drsmooth/man/noel.Rd drsmooth/man/lbcd.Rd drsmooth/man/dunns.format.Rd drsmooth/man/outlier.Rd drsmooth/man/chisquare.Rd drsmooth/man/dichot_smooth.Rd drsmooth/man/shapiro.Rd drsmooth/man/expand.Rd drsmooth/man/dunnetts.format.Rd drsmooth/man/drsmooth.Rd drsmooth/man/prelimstats.Rd drsmooth/man/smooth.Rd

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