leadworker: DNA Damage in Lead Workers

In evident: Evidence Factors in Observational Studies

DNA Damage in Lead Workers

Description

Data from Table 1 of Wu et al. (2002) concerning DNA damage among lead workers compared to controls. In this example, the data have been matched for age and smoking, making 11 matched pairs. Used as an example in Rosenbaum (2021).

Usage

data("leadworker")

Format

A data frame with 22 observations on the following 7 variables.

mset

Matched set indicator, 1, 2, ..., 11

group

1=lead worker, 0=control

age

Age in years

smoking

Smoking, pack-years

bll

Blood lead level, mu-g/dl

dpc

DNA-protein cross-links, percent

id

ID number in the original study, before matching

Details

The outcome, a measure of DNA damage is dpc.

Source

Fang-Yang Wu, Pao-Wen Chang, Chin-Ching Wu and Hsien-Wen Kuo (2002). "Correlations of Blood Lead with DNA-Protein Cross-Links and Sister Chromatid Exchanges in Lead Workers". Cancer Epidemiology, Biomarkers and Prevtion. March 1 2002 11 (3) 287-290.

References

Rosenbaum, Paul R. (2021) <doi:10.1201/9781003039648> Replication and Evidence Factors in Observational Studies. Chapman and Hall/CRC.

Examples

data(leadworker)
boxplot(leadworker$dpc~leadworker$group)

evident documentation built on March 18, 2022, 6:13 p.m.