extraBinomial-package: Extra-binomial approach for pooled sequencing data

In extraBinomial: Extra-binomial approach for pooled sequencing data

Description

This package tests for differences in minor allele frequency between groups and is based on extra-binomial variation model for pooled sequencing data.

Details

Package:	extraBinomial
Type:	Package
Version:	2.1
Date:	2012-07-09
License:	GPL-3

To use the function exbio, simply define two matrices R, R.alt with the same dimensions (rows index SNPs and columns index pools), a vector cc indicating the case and control status, number of chromosomes (n) and then do: exbio(R, R.alt, cc, n) to yield the estimated allele frequencies and p-value based on extra-binomial model.

Author(s)

Xin Yang, Chris Wallace

Maintainer: Xin Yang <[e-mail]>

References

Yang et al. "Extra-binomial variation approach for analysis of pooled DNA sequencing data", under review.

extraBinomial documentation built on May 2, 2019, 2:15 a.m.