epilepsy: Epileptic seizures in clinical trial of drug

In faraway: Functions and Datasets for Books by Julian Faraway

Epileptic seizures in clinical trial of drug

Description

Data from a clinical trial of 59 epileptics. For a baseline, patients were observed for 8 weeks and the number of seizures recorded. The patients were then randomized to treatment by the drug Progabide (31 patients) or to the placebo group (28 patients). They were observed for four 2-week periods and the number of seizures recorded.

Format

A data frame with 295 observations on the following 6 variables.

seizures

number of seizures

id

identifying number

treat

1=treated, 0=not

expind

0=baseline period, 1=treatment period

timeadj

weeks of period

age

in years

Source

Thall, P. F. and S. C. Vail (1990). Some covariance models for longitudinal count data with overdispersion. Biometrics 46, 657-671.

References

Breslow, N. E. and D. G. Clayton (1993). Approximate inference in generalized linear mixed models. Journal of the American Statistical Association 88, 9-25. Diggle, P. J., P. Heagerty, K. Y. Liang, and S. L. Zeger (2002). Analysis of Longitudinal Data (2 ed.). Oxford: Oxford University Press.

Examples

data(epilepsy)
## maybe str(epilepsy) ; plot(epilepsy) ...

faraway documentation built on Aug. 23, 2022, 5:08 p.m.