listerdata: Methylation data for Arabidopsis thaliana

In fdrDiscreteNull: False Discovery Rate Procedures Under Discrete and Heterogeneous Null Distributions

Description

This data set has been analyzed and provided by the listed reference. There are around 22000 cytosines, each of which is under two conditions. For each cytosine under each condition, there is only one replicate. The discrete count for each replicate can be modelled by binomial distribution, and Fisher'e exact test can be applied to assess if a cytosine is differentially methylated. The filtered data "listerdata.RData" contains cytosines whose total counts for both lines are greater than 5 and whose count for each line does not exceed 25.

References

Lister, R., O'Malley, R., Tonti-Filippini, J., Gregory, B. D., Berry, Charles C. Millar, A. H. and Ecker, J. R. (2008). Highly integrated single-base resolution maps of the epigenome in arabidopsis, Cell 133(3): 523-536.

fdrDiscreteNull documentation built on April 25, 2020, 1:11 a.m.