View source: R/sample_size_3arm.R
sample_size_3arm | R Documentation |
Calculate the sample size for each arm in a three-arm trial
sample_size_3arm(kappa, m0, mA, mB, delta, ta, tf, P, diff)
kappa |
the shape parameter of weibull distribution |
m0 |
the median survival time of historical control with respect to both arm A, B and C |
mA |
the median survival time of arm A |
mB |
the median survival time of arm B |
delta |
the hazard ratio of arm C to arm A |
ta |
the accrual duration |
tf |
the follow-up duration |
P |
the chance of correctly selecting the superior arm |
diff |
the equivalence margin |
sample_size_3arm()
returns required sample size for each arm
Chia-Wei Hsu, Haitao Pan, Jianrong Wu
Jianrong Wu, Haitao Pan, Chia-Wei Hsu (2021). "Two-Stage Screened Selection Designs for Randomized Phase II Trials with Time-to-Event Endpoints." Submitted
sample_size_3arm(kappa = 1, m0 = 1, mA = 2, mB = 2, delta = 0.6, ta = 24, tf = 3, P = 0.90, diff = 0) sample_size_3arm(kappa = 1, m0 = 1, mA = 2, mB = 2, delta = 0.6, ta = 24, tf = 3, P = 0.90, diff = 0.25)
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