cells_to_gene_signature: Cells to Gene Signature

In genular: 'Genular' Database API

Cells to Gene Signature

Description

Queries for cells based on given values, fetches genes associated with those cells, and filters for unique gene identifiers based on specified criteria such as fold change. This function streamlines the process of identifying significant gene signatures from cell query results. The function further filters results based on a threshold determined by the mean and standard deviation of foldChange values.

Usage

cells_to_gene_signature(
  queryValues,
  data,
  dataMeta,
  uniqueRowID = "",
  options = list(timeout = 10000)
)

Arguments

queryValues	A vector of query values to search for cells.
data	A data frame containing gene expression data to be mapped.
dataMeta	A data frame containing metadata for each entry in data.
uniqueRowID	The name of the column in dataMeta that uniquely identifies each row.
options	A list of options for the API call, including endpoint and timeout settings.

Value

A list containing data, the final data frame with gene signatures, and mapping, a data frame of gene to cell mappings.

Examples

## Not run: 
cells_to_gene_signature(
  queryValues = c("CL0001054", "CL0002397"),
  data = yourData,
  dataMeta = yourDataMeta,
  uniqueRowID = "yourUniqueIdentifierColumnName"
)

## End(Not run)

genular documentation built on Oct. 19, 2024, 9:07 a.m.