Interval-censored data for times to cytomegalovirus (CMV) shedding in blood and urine

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Description

The cmv data frame is based on an AIDS clinic trial on HIV-infected individuals. The data involve 204 patients who are classified into two groups based on whether patient's CD4 count is below 75 cells per μ l or not. Among the 204 patients, 111 of them had a CD4 count below 75.

Usage

1

Format

A data frame with 204 observations on the following 6 variables.

patient

patient id

lb

left end point of an censoring interval for time to CMV shedding in blood

rb

right end point of an censoring interval for time to CMV shedding in blood

lu

left end point of an censoring interval for time to CMV shedding in urine

ru

right end point of an censoring interval for time to CMV shedding in urine

cd4ind

group indicator if patient's baseline CD4 count is below 75 (1 for below 75 and 0 otherwise)

Details

The survival times are time to the presence of CMV in blood and ullrine, respectively. The censoring intervals are in the format of (l_b, r_b] and (l_u, r_u]. For CMV in blood, there are 7 left-censored, 23 interval-censored, and 174 right-censored, but no exact observations. For CMV in urine, there are 49 left-censored, 67 interval-censored, and 88 right-censored, but no exact observations.

Source

J. Sun (2006), "The Statistical Analysis of Interval-censored Failure Time Data", Springer.

References

W. B. Goggins and D. M. Finkelstein (2000), "A proportional hazards model for multivariate interval-censored failure time data", Biometrics, 56: 940-943.

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