adjust_weights_parametric_util: Calculate adjusted hypothesis weights for parametric tests

In graphicalMCP: Graphical Multiple Comparison Procedures

Calculate adjusted hypothesis weights for parametric tests

Description

An intersection hypothesis can be rejected if its p-values are less than or equal to their adjusted significance levels, which are their adjusted hypothesis weights times \alpha. For Bonferroni tests, their adjusted hypothesis weights are their hypothesis weights of the intersection hypothesis. Additional adjustment is needed for parametric tests:

• Parametric tests for adjust_weights_parametric(),

  • Note that one-sided tests are required for parametric tests.

Usage

c_value_function(
  x,
  hypotheses,
  test_corr,
  alpha,
  maxpts = 25000,
  abseps = 1e-06,
  releps = 0
)

solve_c_parametric(
  hypotheses,
  test_corr,
  alpha,
  maxpts = 25000,
  abseps = 1e-06,
  releps = 0
)

adjust_weights_parametric_util(
  matrix_weights,
  matrix_intersections,
  test_corr,
  alpha,
  test_groups,
  maxpts = 25000,
  abseps = 1e-06,
  releps = 0
)

Arguments

x	The root to solve for with stats::uniroot().
hypotheses	A numeric vector of hypothesis weights. Must be a vector of values between 0 & 1 (inclusive). The sum of hypothesis weights should not exceed 1.
test_corr	(Optional) A numeric matrix of correlations between test statistics, which is needed to perform parametric tests using adjust_weights_parametric(). The number of rows and columns of this correlation matrix should match the length of p.
alpha	(Optional) A numeric value of the overall significance level, which should be between 0 & 1. The default is 0.025 for one-sided hypothesis testing problems; another common choice is 0.05 for two-sided hypothesis testing problems. Note when parametric tests are used, only one-sided tests are supported.
maxpts	(Optional) An integer scalar for the maximum number of function values, which is needed to perform parametric tests using the mvtnorm::GenzBretz algorithm. The default is 25000.
abseps	(Optional) A numeric scalar for the absolute error tolerance, which is needed to perform parametric tests using the mvtnorm::GenzBretz algorithm. The default is 1e-6.
releps	(Optional) A numeric scalar for the relative error tolerance as double, which is needed to perform parametric tests using the mvtnorm::GenzBretz algorithm. The default is 0.

Value

• c_value_function() returns the difference between \alpha and the Type I error of the parametric test with the c value of x, adjusted for the correlation between test statistics using parametric tests based on equation (6) of Xi et al. (2017).

• solve_c_parametric() returns the c value adjusted for the correlation between test statistics using parametric tests based on equation (6) of Xi et al. (2017).

References

Xi, D., Glimm, E., Maurer, W., and Bretz, F. (2017). A unified framework for weighted parametric multiple test procedures. Biometrical Journal, 59(5), 918-931.

See Also

adjust_weights_parametric() for adjusted hypothesis weights using parametric tests.

graphicalMCP documentation built on June 8, 2025, 11:19 a.m.