A large quad-variate data set was simulated assuming an underlying Cholesky model, with 5000 observations per trait and high polygenicity (20,000 SNPs per genetic factor). Genetic trait variances were set to 0.30, 0.60, 0.60 and 0.70 respectively, and residual variances to 0.70, 0.40, 0.40 and 0.30. The data set is described in full, including genetic and residual covariances, in the vignette. A 4-variate Cholesky model was fitted to the data as described in the vignette and the output has been saved in fit.large.RData.
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gsem.fit output (a list object)
input parameters
fitted formula
optimisation output
fitted gsem model
variance covariance matrix
Number of phenotypes
Number of observations across all phenotypes
Number of observations per phenotype
Number of individuals with at least one phenotype
gsem model
constraint
phenotype names
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