Man pages for gsMeanFreq
Group Sequential Clinical Trial Designs for Composite Endpoints

Apply.calendar.censoringFunction to apply a given calendar time as effective...
Apply.calendar.censoring.2Function to apply a given calendar time as effective...
find.beta.trtFunction to solve for treatment effect size given target...
find.cFunction to solve for a group sequential critical value at a...
find.Delta.given.powerFunction to solve for the mean frequency effect size given...
find.lambda_0.given.DeltaFunction to solve for the baseline recurrent event rate given...
find.lambda_0.given.mu0Function to solve for the baseline recurrent event rate given...
OBFO'Brien-Flemming error spending function.
OneSample.Estimator.sequentialFunction to estimate the one-sample mean frequency under a...
Onesample.generate.sequentialFunction to simulate one-sample composite endpoint data under...
Solve.beta.given.powerFunction to solve for the treatment effect parameter to...
True.muFunction to calculate the true value of the mean frequency...
TwoSample.Boundary.TTFEFunction to calculate the sequential rejection boundaries for...
TwoSample.Constant.GTFunction to compute calibration constants for the two-sample...
TwoSample.Constant.LRFunction to compute calibration constants for the two-sample...
TwoSample.Estimator.GT.sequentialFunction to calculate the two-sample generalized-t statistic...
TwoSample.Estimator.LR.sequentialFunction to calculate the two-sample generalized log-rank...
TwoSample.Estimator.TTFE.sequentialFunction to calculate the Z statistics and variance for the...
TwoSample.generate.sequentialFunction to simulate two-sample composite endpoint data under...
TwoSample.Q.Cov.Estimator.Sequential.GTFunction to calculate stage-wise test statistics, variances,...
TwoSample.Q.Cov.Estimator.Sequential.LRFunction to calculate stage-wise test statistics, variances,...
TwoSample.Wald.and.BoundaryFunction to calculate the Wald statistics and group...
TwoSample.Z.Var.Estimator.Sequential.TTFEFunction to calculate the two-sample time-to-first-event...
gsMeanFreq documentation built on Feb. 17, 2026, 1:07 a.m.