hacksig: A Tidy Framework to Hack Gene Expression Signatures

A collection of cancer transcriptomics gene signatures as well as a simple and tidy interface to compute single sample enrichment scores either with the original procedure or with three alternatives: the "combined z-score" of Lee et al. (2008) <doi:10.1371/journal.pcbi.1000217>, the "single sample GSEA" of Barbie et al. (2009) <doi:10.1038/nature08460> and the "singscore" of Foroutan et al. (2018) <doi:10.1186/s12859-018-2435-4>. The 'get_sig_info()' function can be used to retrieve information about each signature implemented.

Package details

AuthorAndrea Carenzo [aut, cre] (<https://orcid.org/0000-0001-6804-9984>), Loris De Cecco [aut] (<https://orcid.org/0000-0002-7066-473X>), Federico Pistore [aut]
MaintainerAndrea Carenzo <andrea.carenzo@gmail.com>
LicenseMIT + file LICENSE
URL https://github.com/Acare/hacksig
Package repositoryView on CRAN
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hacksig documentation built on Dec. 2, 2021, 9:07 a.m.