inferMM-package: inferMM: Variance-Aware Michaelis-Menten Estimation and...

inferMM-packageR Documentation

inferMM: Variance-Aware Michaelis-Menten Estimation and Inference

Description

The inferMM package provides variance-aware tools for Michaelis-Menten estimation, clustered repeated-measurement analysis, model screening, grouped curve analysis, simulation, and prediction. Single-curve fits and grouped screening accept user-defined fixed positive variance functions in addition to the built-in variance shapes. An optional higher-moment estimator fits independent curves using working skewness and kurtosis, with joint sandwich or model-based covariance.

Details

The package focuses on enzyme-kinetic settings where measurement variability may increase with substrate concentration, making standard homoscedastic nonlinear least squares inadequate for interval estimation and uncertainty quantification.

See Also

fit_mm, fit_mm_moments, cluster_mm, report_mm, screen_mm, group_mm, simulate_mm_data, variance_function


inferMM documentation built on Oct. 30, 2026, 9:06 a.m.