ingres-package: ingres: Infer Gene Probabilistic Boolean Networks from...

In ingres: Infer Gene Probabilistic Boolean Networks from Single-Cell Data

ingres: Infer Gene Probabilistic Boolean Networks from Single-Cell Data

Description

Given a gene regulatory boolean network and a RNA-seq dataset, this package computes protein activity normalised enrichment scores using 'VIPER', and then produces a probabilistic network using the scores as probabilities for fixed node activation or deactivation, in addition to the original Boolean functions. For more information, refer to the preprint: Victori and Buffa (2022) <doi:10.1101/2022.09.04.506528>.

Author(s)

Maintainer: Pedro Victori [e-mail] (ORCID)

Authors:

• Francesca M. Buffa [e-mail] (ORCID)

See Also

Useful links:

• https://github.com/CBigOxf/ingres

• https://cbigoxf.github.io/ingres/

• Report bugs at https://github.com/CBigOxf/ingres/issues

ingres documentation built on Sept. 14, 2022, 9:05 a.m.