Description Usage Arguments Details Value See Also Examples
Function event
simulates the events base on a recruitment scenario simulated by function recruitment
.
1 | event(r, er, dr, du)
|
r |
recruitment scenario calculated with function |
er |
event rate during the clinical trail. |
dr |
drop-out rate during the clinical trail. |
du |
duration of the clinical trail in weeks. |
event
simulates the events based on a given recruitment scenario.
The function assumes an exponential distribution for the event probability with a common event rate for all subjects (er
).
The drop-out rate may be included. For the probability of an drop-out, treatment
assumes an exponential distribution with a common rate dr
.
It is assumed that the even and drop-out time are independent of each other.
event
returns a list of vectors with the following components:
events
a vector with the (cumulative) number of frist events (events before drop-out)
drops
a vector with the (cumulative) number of patients who droped out of the trail before the first event
weeksOfEvent
a vector with the corresponding trial week when patients have experienced the first event
(with start of site openings as reference start)
recruitment
for simulating recruitment scenarios;
eventCourse
for plots of recruitment and event scenarios;
1 2 3 4 5 | x=recruitment(nc=Inf,ns=Inf,cw=4,sw=2,sf=0.3,tb=4,en=400)
y=event(r=x,er=0.12,dr=0.08,du=50)
x=recruitment(nc=Inf,ns=Inf,cw=4,sw=2,sf=0.3,tb=4,en=400)
y=event(r=x,er=0.12,dr=0.08,du=50)
|
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